Hemoglobin A1C
Order Code: A1C
Epic Lab Code: LAB90
Order Form: A-1a General Lab or Epic Req
Chemistry
6240 RCP
356-3527
Specimen:
Whole Blood
Collection Medium:
Lavender top tube 3 mL (EDTA)
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL; lavender top or 2 lavender microtubes for pediatrics
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Analytic Time:
1 hour (upon receipt in laboratory)
Reference Range:
4.8 - 6.0%
Glycemic control guidelines:
  Non-diabetic <6%
  Goal <7%
  Therapeutic action >8%
Test Limitations:
Rheumatoid factor less than 750 IU/mL and ascorbic acid less than 50 mg/dL do not interfere. In hemolytic anemia and iron deficiency anemia, the average age of erythrocytes is altered. Caution should be used when interpreting the HbA1c results from patients with these conditions (2, 3). This assay is not useful in judging day-to-day glucose control and should not be used to replace daily home testing of urine and blood glucose. References: (1) Glick MR, Ryder KW, Jackson SA. Graphical Comparisons of Interferences in Clinical Chemistry Instrumentation. Clin Chem 1986;32:470-474. (2) Greiling H, Gressner AM, eds. Lehrbuch der Klinischen Chemie und Pathobiochemie, 3rd ed. Stuttgart/New York: Schattauer, 1995:279. (3) Bessis M. Living Blood Cells and their Ultrastructure. Berlin: Springer-Verlag; 1973.
Methodology:
Turbidometric Immunoinhibition
CPT Code:
83036