Fluorescence In-Situ Hybridization (FISH-Prenatal-Aneuploidy/Microdeletion)
Epic Lab Code: CYT54
Order Form: C-12 Cytogenetics Request or Epic Req
Shivanand R. Patil Cytogenetics & Molecular Laboratory (Dept. of Pediatrics)
W-101 GH
356-3877 (Laboratory)
Specimen:
Amniocytes, Chorionic Villi
Minimum:
Specimen obtained by referring staff physician. Collect specimen using sterile technique. DO NOT FREEZE OR CENTRIFUGE THE SPECIMEN. Contact the Cytogenetics lab with questions. Label tubes with patient name and medical record number.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection.
Specimen Instructions:
Provide details of clinical information. If a specimen is collected over the weekend, please page the technologist on call by dialing 1-888- 533-0186. When it stops ringing, enter your phone number, the '#' sign, and hang up.
Testing Schedule:
Specimens accepted in the lab Monday-Friday, 0800-1700. After hours specimens should be taken to specimen control and a message left on the lab voice mail. In the case of an emergency, follow the instructions on the lab voice mail.
Analytic Time:
Preliminary results will be reported within two-three days and the final written report in five days for the aneuploidy screening. For submicroscopic rearrangement, preliminary results will be reported in eight days and the final written report will be available in two weeks.
Reference Range:
Male: X and Y probe signals Female: two X probe signals The reference range varies for each probe (set).
Comments:
This test can be used as an adjunct to chromosomal analysis for aneuploidy screening on interphase nuclei and on chromosomes for detection of submicroscopic/cryptic rearrangements in certain congenital disorders. Probes currently available include: Aneuvysion (aneuploidy screening for 21,18,13,X and Y), TUPLE 1 (del 22q for CHD). Call laboratory for additional information or requests. Shivanand R. Patil Cytogenetics & Molecular Laboratory Website
Methodology:
Fluorescence In-Situ Hybridization (FISH)
CPT Code:
88235, 88271 (88273), 88275, 88365
 
See also:
Chromosomal Analysis, Amniotic Fluid
 
See Additional Information:
Cytogenetics and Molecular Testing