Deoxycorticosterone
| Order Code: | DOC |
| Epic Lab Code: | LAB2991 |
| Order Form: | A-1a Miscellaneous Request or Epic Req |
Commercial Mail-out Laboratory
6240 RCP
356-3527
6240 RCP
356-3527
Specimen:
Serum
Collection Medium:
 |
| Red top tube |
Minimum:
Preferred Minimum: 3.0 mL serum
Absolute Minimum: 1.1 mL serum (allows for one run only at reference lab).
Absolute Minimum: 1.1 mL serum (allows for one run only at reference lab).
Rejection Criteria:
No gels or specimens received room temperature
Analytic Time:
Set-up at reference laboratory on Tuesday; reports within 2 days from
set-up.
Reference Range:
Adult Male 3.5-11.5 ng/dL
Adult Female
Follicular 1.5-8.5 ng/dL
Luteal 3.5-13.0 ng/dL
Pregnancy
First Trimester 5-25 ng/dL
Second Trimester 10-75 ng/dL
Third Trimester 30-110 ng/dL
Post-ACTH Stimulation 60 Minutes
Males and Premenopausal
Females (Follicular Phase) 14-33 ng/dL
Pediatric
ACTH Stimulation Baseline (ng/mL) 60 Minutes
(ng/mL)
<1 Year 7-57 20-160
1-5 Years 4-49 26-140
6-12 Years Male 9-34 33-140
6-12 Years Female 2-13 19-61
Tanner Stages II-III
Male 4-30 12-74
Female 2-12 13-63
Tanner Stages IV-V
Male 5-14 19-46
Female 5-10 23-40
Comments:
DOC is a precursor of corticosterone and aldosterone. The elevations of
DOC observed in patients with 11-hydroxylase deficiency (the second
leading cause of congenital adrenal hyperplasia) may reflect the
hypertension observed. Patients with DOC-secreting tumors also exhibit
hypertension.
Methodology:
Extraction, Chromatography, Radioimmunoassay (RIA)
CPT Code:
82633