Specimen

Urine More information

Collection Medium:

Minimum:

5 mL requested
Adult minimum (0.5 mL) and Peds minimum (0.5 mL) of urine from random 
or 24 hour collection in a plastic container, refrigerate during 
collection.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after
collection period is completed.

Analytic Time:

2 working days (upon receipt)

Reference Range:

Components                    Reference Interval
Methylmalonic Acid, Urine    0.0-3.6 mmol/mol CRT

Creatinine (24-hour)        Male                        Female
                    3-8 yrs:  140-700  mg/d     3-8 yrs:  140-700  mg/d
                    9-12 yrs: 300-1300 mg/d     9-12 yrs: 300-1300 mg/d
                   13-17 yrs: 500-2300 mg/d    13-17 yrs: 400-1600 mg/d
                   18-50 yrs: 1000-2500mg/d    18-50 yrs: 700-1600 mg/d
                   51-80 yrs: 800-2100 mg/d    51-80 yrs: 500-1400 mg/d
                   81 yrs+:   600-2000 mg/d    81 yrs+:   400-1300 mg/d

Comments:

Elevated urinary methylmalonic acid is an early and sensitive
indicator of vitamin B12 (cobalamin) deficiency.

The most important aspect of specimen preservation is adequate
refrigeration during collection, storage and transport.

Methodology:

High Performance Liquid Chromatography/Tandem Mass Spectrometry

CPT Code:

83921

See Additional Information:
Urine Tests Requiring Preservatives, Refrigeration or Special Containers