Methylmalonic Acid, Quantitative
Order Code: MMAUR
Epic Lab Code: LAB3601
Order Form: A-1a Miscellaneous Request or Epic Req
Commercial Mail-out Laboratory
6240 RCP
356-3527
Specimen:
Urine More information
Collection Medium:
Urine - 24 hour/timed plastic urine container
Minimum:
Preferred Minimum: 4 mL urine
Absolute Minimum: 0.5 mL urine

24 hour collection in a plastic container, refrigerate during collection is also accepted by the reference lab.
Rejection Criteria:
Room temperature specimens.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection period is completed.
Analytic Time:
2 working days upon receipt at reference laboratory
Reference Range:
Components Reference Interval Methylmalonic Acid, Urine 0.0-3.6 mmol/mol CRT Creatinine (24-hour) Male Female 3-8 yrs: 140-700 mg/d 3-8 yrs: 140-700 mg/d 9-12 yrs: 300-1300 mg/d 9-12 yrs: 300-1300 mg/d 13-17 yrs: 500-2300 mg/d 13-17 yrs: 400-1600 mg/d 18-50 yrs: 1000-2500mg/d 18-50 yrs: 700-1600 mg/d 51-80 yrs: 800-2100 mg/d 51-80 yrs: 500-1400 mg/d 81 yrs+: 600-2000 mg/d 81 yrs+: 400-1300 mg/d
Comments:
Elevated urinary methylmalonic acid is an early and sensitive indicator of vitamin B12 (cobalamin) deficiency. The most important aspect of specimen preservation is adequate refrigeration during collection, storage and transport.
Methodology:
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
CPT Code:
83921
 
See Additional Information:
Urine Tests Requiring Preservatives, Refrigeration or Special Containers