Cytomegalovirus Antibody, IgM Class
Order Code: CMVM
Epic Lab Code: LAB938
Order Form: A-1a General Lab or Epic Req
Chemistry
6240 RCP
356-3527
Specimen:
Serum
Collection Medium:
Red top tube
Minimum:
3 mL; red top
Rejection Criteria:
Plasma specimens
Testing Schedule:
Test performed on Monday, Wednesday and Friday.
Turn Around Time:
3 days
Reference Range:
See Interpretive Data
Interpretive Data:
Negative - No significant level of detectable CMV IgM antibody
Equivocal - Repeat testing in 7-14 days may be helpful
Positive - IgM antibody to CMV detected, which may indicate a current or recent CMV infection.
Comments:
Low levels of CMV IgM antibodies may occasionally persist for more than 12 months post-infection.
Test Limitations:
In immunocompromised patients, CMV serology (IgG or IgM antibody titers) may not be reliable and may be misleading in the diagnosis of acute or reactivation CMV disease. Positive test results may not be valid in persons who have received blood transfusions or other blood products within the past several months. A negative result in the CMV IgM assay does not preclude the possibility of recent primary CMV infection. Use of the CMV IgM assay in cord blood or neonatal samples has not been validated. Serum samples with total IgG concentrations of greater than or equal to 20 mg/mL may cause interference in the CMV IgM assay due to incomplete absorption of the IgG.
Methodology:
Enzyme Linked Fluorescent Immunoassay (ELFA)
CPT Code:
86645