Specimen

Tumor Tissue

Minimum:

Specimen obtained aseptically according to your protocol.  Collect 
specimen using sterile technique. DO NOT FREEZE OR CENTRIFUGE THE 
SPECIMEN.  This analysis can be done on interphase nuclei or on 
metaphase cells.  Contact the Cytogenetics Lab with questions.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection.

Specimen
Instructions:

Provide details of clinical information.  If a specimen is collected 
over the weekend, please page the technologist on call by dialing 
1-888-533-0186.  When it stops ringing, enter your phone number, the 
'#' sign, and hang up.

Testing Schedule:

Specimens accepted in the lab Monday-Friday, 0800-1700.  After hours 
specimens should be taken to specimen control and a message left on the 
lab voice mail.  In the case of an emergency, follow the instructions 
on the lab voice mail.

Analytic Time:

Preliminary results will be reported within 2-3 days and final results 
within 1-2 weeks.

Reference Range:

Male:  X and Y probe signals          Female:  two X probe signals
For autosomes, the reference range varies for each probe (set).  
Suitable for interphase and metaphase analysis.  Call lab for 
information.

Comments:

This test can be used for screening of sex chromosomes, for monosomies 
(eg., 5, 7, etc.), for trisomies (eg., +4, +8, +11, +12, +13, +14, +18, 
+19, +21, +22, etc.) or for detection of the gene fusion resulting from 
translocations in solid tumors.

If the desired FISH probe is not listed, call the laboratory.


Cytogenetics Laboratory Web Site

Methodology:

Fluorescence In-Situ Hybridization (FISH)

CPT Code:

88239, 88271, 88275, 88365

See also:
Chromosomal Analysis, Bone Marrow (for acquired and constitutional abnormalities)

See Additional Information:
Cytogenetics Testing