C4 Complement Component, Plasma

C4 Complement Component

Order Code:	C4
Epic Lab Code:	LAB151
Order Form:	A-1a General Lab or Epic Req

Chemistry
6240 RCP
356-3527

Specimen:

Plasma

Collection Medium:

Plasma Separator Tube

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3 mL whole blood from light green top tube or 1 microtainer

Rejection Criteria:

Specimens collected in Sodium Citrate tubes.

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Analytic Time:

1 hour (upon receipt in laboratory)

Reference Range:

16-47 mg/dL

Comments:

Measures concentration by specific antibody. If cryoglobulin present or suspected, collect specimen as directed for 'Cryoglobulin, Serum'.

Test Limitations:

Criterion: Recovery within plus or minus 10% of initial value. Icterus: No significant interference up to an I index of 60 (approximate conjugated and unconjugated bilirubin concentration: 60 mg/dl or 1026 umol/l). Hemolysis: No significant interference up to an H index of 900 (approximate hemoglobin concentration: 900 mg/dl or 559 umol/l) Lipemia (Intralipid): No significant interference up to an L index of 1000 (approximate triglycerides concentration: 2000 mg/dl or 22.8 mmol/l). There is poor correlation between turbidity and triglycerides concentration. Rheumatoid factors up to 1200 IU/ml do not interfere. No high-dose hook effect is seen up to a C4 concentration of 500 mg/dl. Monoclonal gammopathy sera of the IgA or IgM type can interfere with the C4 determination.

Methodology:

Immunoturbimetric

CPT Code:

86160