The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


C-Reactive Protein (CRP)
Order Code: CRP
Epic Lab Code: LAB149
Order Form: A-1a General Lab or Epic Req
  Chemistry
6240 RCP
356-3527
Specimen:
Plasma
Collection Medium:
Plasma separator tube
Alternate
Collection Media:
Call laboratory for additional acceptable specimen collection 
containers.
Minimum:
2 ml whole blood from light gr een top tube or 1 light green microtube 
for pediatric patients
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Analytic Time:
1 hour (upon receipt in laboratory)
Reference Range:
<0.5 mg/dl
Test
Limitations:
Criterion: Recovery within plus or minus 10% of initial values.

Icterus: No significant interference up to an I index of 60 
(approximate conjugated and unconjugated bilirubin concentration: 60 
mg/dl or 1026 umol/l).

Hemolysis: No significant interference up to an H index of 950. 
(approximate hemoglobin concentration: 700 mg/dl or 435 umol/l )

Lipemia (Intralipid): No significant interference up to an L index of 
1700 (approximate triglyceride concentration: 2000 mg/dl or 22.8 
mmol/l).
There is poor correlation between turbidity and triglyceride 
concentration.

Rheumatoid factors less than 1200 IU/ml do not interfere.

A high-dose hook effect may occur at CRP concentrations greater than 50 
mg/dl.
Methodology:
Immunoturbidometric
CPT Code:
86140

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Updated: 11/03/2009

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.