Beta-2 Transferrin
Order Code: B2TD
Epic Lab Code: LAB2708
Order Form: A-1a Miscellaneous Request or Epic Req
Commercial Mail-out Laboratory
6240 RCP
356-3527
Specimen:
Serum AND Aural or Nasal
Collection Medium:
Red top tube
Minimum:
Adult preferred minimum: 2 mL serum AND 2 mL aural or nasal fluid in a CSF container Adult absolute minimum: 0.5 mL serum AND 1 mL aural or nasal fluid in a CSF container Pediatric minimum: 0.5 mL of serum AND 1.0 mL of aural or nasal fluid in a CSF container
Rejection Criteria:
Plasma specimens
Specimen Instructions:
MUST: Submit two samples types (serum AND aural or nasal fluid).
Analytic Time:
4 working days upon receipt at reference laboratory
Reference Range:
None detected Beta-2 transferrin is not detected in normal serum, tears, saliva, sputum, nasal, aural fluid, or endolymph by this method.
Interpretive Data:
Detection of a beta-2 transferrin band by IFE (Immunofixation Electrophoresis) is diagnostic for the presence of CSF. This test is a consideration in the differential diagnosis for CSF otorrhea or CSF rhinorrhea. Beta-2 transferrin is not detected in normal serum, ears, saliva, sputum, nasal, aural fluid, or endolymph by this method.
Test Limitations:
The beta-2 transferrin protein assay by IFE methodology is not a reliable method for detecting human perilymph due to the low sensitivity of the assay.
Methodology:
Immunofixation Electrophoresis
CPT Code:
86334 IFE Serum, 86335 IFE Fluid