MLH1 Promoter Methylation, Paraffin
| Label Mnemonic: | MLH1PCR |
| Epic code: | LAB8449 |
| Downtime form: | A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Tumor Tissue
Specimen
Instructions:
Formalin fix (10 percent neutral buffered formalin) and paraffin embed
tissue. Protect from excessive heat. Transport tissue block or 5
unstained 5-micron slides. (Min: 3 slides) Transport block and/or slide
(s) in a tissue transport kit. Store and send at room temperature.
Collection Medium:
) |
| Tissue Block |
Rejection Criteria:
Frozen specimens. Specimens fixed/processed in alternative fixatives
(alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). Decalcified
specimens.
Turn Around
Time:
10-12 days upon receipt at reference laboratory
Interpretive Data:
Refer to report.
Comments:
This test distinguishes between Lynch syndrome and sporadic tumors
with loss of MLH1.
Methodology:
Real-Time Polymerase Chain Reaction/Fluorescence Resonance Energy
Transfer
CPT Code:
88381, 81288