MPL codon 515 Mutation
| Label Mnemonic: | MPL |
| Epic code: | LAB8118 |
| Downtime form: | A-1a Doctor/Provider Orders - Pathology Molecular |
Molecular Pathology
6240 RCP
384-9568
6240 RCP
384-9568
Specimen(s):
Blood
Collection Medium:
 |
| Pink top tube 6 mL (K2-EDTA) |
Minimum:
Adults: 3 mL whole blood. Testing requires a dedicated collection tube.
Delivery Instructions:
Room temperature for up to 24 hours, then refrigerate
the whole blood if it is necessary to be held overnight,
weekends or holidays.
Testing Schedule:
Weekly
Turn Around
Time:
7-10 working days
Interpretive Data:
Mutation not detected
Comments:
MPL exon 10 coding sequence is amplified by polymerase chain reaction
(PCR) and sequenced in both directions using next generation
sequencing. The reference sequence with which this patient's DNA
sequence is compared is NM_005373.1. The test will detect codon 505
and 515 mutations.
Methodology:
Massively parallel next generation sequencing on DNA
CPT Code:
81479