MPL codon 515 Mutation
| Label Mnemonic: | MPLBM |
| Epic code: | LAB8119 |
| Downtime form: | A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Molecular Pathology
6240 RCP
384-9568
6240 RCP
384-9568
Specimen(s):
Bone Marrow Aspirate
Collection Medium:
 |
| Pink top tube 6 mL (K2-EDTA) |
Minimum:
Adults: 3 mL bone marrow aspirate. Testing requires a dedicated
collection tube.
Testing Schedule:
Weekly
Turn Around
Time:
7-10 days upon receipt
Reference Range:
Mutation not detected
Comments:
MPL exon 10 coding sequence is amplified by polymerase chain reaction
(PCR) and sequenced in both directions using next generation
sequencing. The reference sequence with which this patient's DNA
sequence is compared is NM_005373.1. The test will detect codon 505
and 515 mutations.
Methodology:
Massively parallel next generation sequencing on DNA
CPT Code:
81479