Acylglycines, Quantitative
| Order Code: | ACYLG |
| Epic Lab Code: | LAB2538 |
| Order Form: | A-1a Miscellaneous Request or Epic Req |
Commercial Mail-out Laboratory
01250 PFP
356-3527
01250 PFP
356-3527
Specimen(s):
Random Urine
Collection Medium:
) |
| Yellow top conical tube (no additive) |
Minimum:
Preferred Minimum: 10 mL random urine
Absolute Minimum: 4 mL random urine
Absolute Minimum: 4 mL random urine
Specimen
Instructions:
1. Patient's age is required.
2. Include family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.
2. Include family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.
Turn Around
Time:
5 days upon receipt at reference laboratory (not reported on Saturday
or Sunday)
Reference Range:
Control Values
Results Expressed as mg/g Creatinine
Range
Ethylmalonic Acid 0.5-20.2
2-Methylsuccinic Acid 0.4-13.8
Glutaric Acid 0.6-15.2
Isobutyrylglycine 0.0-11.0
n-Butyrylglycine 0.1- 2.1
2-Methylbutyrylglycine 0.3- 7.5
Isovalerylglycine 0.3-14.3
n-Hexanoylglycine 0.2- 1.9
n-Octanoylglycine 0.1- 2.1
3-Phenylpropionylglycine 0.0- 1.1
Suberylglycine 0.0-11.0
trans-Cinnamoylglycine 0.2-14.7
Dodecanedioic Acid (12 DCA) 0.0- 1.1
Tetradecanedioic Acid (14 DCA) 0.0- 1.0
Hexadecanedioic Acid (16 DCA) 0.0- 1.0
Interpretive Data:
When abnormal results are detected, a detailed interpretation is given,
including an overview of the results and of their significance; a
correlation to available clinical information; elements of differential
diagnosis; recommendations for additional biochemical testing and in
vitro confirmatory studies (enzyme assay, molecular analysis); name and
phone number of key contacts who may provide these studies at the
reference laboratory or elsewhere; and a phone number to reach one of
the laboratory directors in case the referring physician has additional
questions.
Comments:
Freeze urine as soon as possible; this task is performed by Specimen
Control in Pathology. Avoid dilute urine when possible. Clinical
information is needed for appropriate interpretation. Additional
required information includes age, gender, diet (e.g., TPN therapy),
drug therapy, and family history.
Methodology:
Gas Chromatography-Mass Spectrometry (GC-MS) Stable Isotope Dilution
Analysis
CPT Code:
82544