The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK

Drugs of Abuse Panel, Meconium - Screen with Reflex to Confirmation/Quantitation
Order Code: MEC9
Order Form: A-1a Miscellaneous Request or IPR Req 		  Commercial "Mail-out" Laboratory
6240 RCP
356-3527 
Specimen
 
Meconium
Collection Medium:
Meconium 


Minimum:


Meconium. All meconium (blackish material) excreted until milk/formula 
based stool (yellow-green) appears.

All meconium available (4 g is preferred) at 20-25(Min: 2 g or 3/4 inch 
cube on each side)


Analytic Time:


Within 4 days
Negative: 1-2 days; Positive: 2-4 days


Reference Range:


                  Drugs Covered and Cutoff Concentrations
Drug                             Screen     Confirmation
Marijuana                        30 ng/g       10 ng/g
  9-carboxy-THC
  11-hydroxy-THC
Cocaine                          30 ng/g       20 ng/g
  Cocaine
  Benzoylecgonine
  m-hydroxybenzoylecgonine
  Cocaethylene
Opiates                          30 ng/g        2 ng/g
  Codeine
  Morphine
  6 - acetylmorphine
  Hydrocodone
  Hydromorphone
  Oxycodone
Phencyclidine                    15 ng/g       10 ng/g
Amphetamines                     30 ng/g       20 ng/g
  Amphetamine
  Methamphetamine
  Methylenedioxymethamphetamine (MDMA-Ecstasy)
  Methylenedioxyamphetamine (MDA)
Barbiturates                     75 ng/g       50 ng/g
  Butalbital
  Amobarbital
  Pentobarbital
  Secobarbital
  Phenobarbital
Methadone and metabolite         40 ng/g       10 ng/g
Benzodiazepines                  75 ng/g       20 ng/g
  Alprazolam
  Alpha-hydroxyalprazolam
  Clonazepam
  7-Amino Clonazepam
  Diazepam
  Alpha-hydroxyethylflurazepam
  Lorazepam
  Nordiazepam
  Oxazepam
  Temazepam
  Alpha-hydroxytriazolam
Propoxyphene and metabolite      75 ng/g       10 ng/g


Interpretive Data:


For medical purposes only; not valid for forensic use.


Comments:


Screen-positive specimens are automatically confirmed by GC/MS or 
LC-MS/MS, additional charges may apply.

If specimen screens positive, then the confirmation test for the drug 
class will be added.


Methodology:


Enzyme-Linked Immunoassay/Gas Chromatography-Mass Spectrometry/Liquid 
Chromatography-Tandem Mass Spectrometry


CPT Code:


80101 x9 Screen; if positive add appropriate CPT code for drug 
confirmed: 82542 Marijuana; 82520 Cocaine; 83925 Opiates; 83992 
Phencyclidine; 82145 Amphetamines; 82205 Barbiturates; 83840 Methadone; 
80154 Benzodiazapine; 83925 Propoxyphene




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Updated: 04/24/2008

Note: The information contained in this handbook is  
            for use by personnel of University of Iowa Health Care. 
            No other use is implied or intended.