The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK

First Screen
Order Code: FIRST
Order Form: A-1a Miscellaneous Request or IPR Req 		  Commercial "Mail-out" Laboratory
6240 RCP
356-3527 
Specimen
 
Serum
Collection Medium:
Red top tube 


Minimum:


2 mL of serum


Analytic Time:


3 working days


Comments:


First Trimester Screening:
FirstScreen screens for fetal Down syndrome and trisomy 18 between 10 
weeks / 3 days and 13 weeks / 6 days (10.4-13.9 weeks, CRL = 39-84 mm). 
Two biochemical markers, pregnancy associated plasma protein (PAPP-A) 
and human chorionic gonadotropin (hCG), and the nuchal translucency 
(NT) ultrasound measurement are combined to provide a risk assessment 
in the first trimester.


Test
Limitations:


The reference laboratory will only accept NT measurements from 
sonographers who have been certified by the Fetal Medicine Foundation 
(FMF) or the Nuchal Translucency Quality Review Program (NTQR).


CPT Code:


84163, 84702




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Updated: 03/28/2008

Note: The information contained in this handbook is  
            for use by personnel of University of Iowa Health Care. 
            No other use is implied or intended.