Rubella Antibody, IgG, Plasma

Order Code:	RUBEIGG
Epic Lab Code:	LAB4835
Order Form:	A-1a Miscellaneous Request or Epic Req

Chemistry
6240 RCP
356-3527

Specimen:

Plasma

Collection Medium:

Plasma Separator Tube

Minimum:

3 mL whole blood in light green top tube or TWO microtainers.

Rejection Criteria:

Heat-inactivated, hemolyzed, or contaminated specimens.

Specimen Instructions:

Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent."

Analytic Time:

1 hour (upon receipt in laboratory)

Reference Range:

Less than 5 IU/mL: Negative - No significant level of detectable rubella IgG antibody. 5-9 IU/mL: Equivocal - Repeat testing in 10-14 days may be helpful. 10 IU/mL or greater: Positive - IgG antibody to rubella detected, which may indicate a current or previous exposure/immunization to rubella.

Interpretive Data:

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Test Limitations:

Hemolysis: No significant interference up to an H index of 5600 (approximate hemoglobin concentration: 5600 mg/dL).

Lipemia: No significant interference up to an L index of 1500 (approximate triglycerides concentration: 3000 mg/dL). Note there is poor correlation between turbidity and triglyceride concentration.

Icterus: No significant interference up to an I index of 30 (approximate conjugated and unconjugated bilirubin concentration: 30 mg/dL).

Methodology:

Chemiluminescent Immunoassay

CPT Code:

86317