Mucopolysaccharides, Quantitation

Label Mnemonic:	MUCPU
Epic code:	LAB7439
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Random Urine

Specimen Instructions:

Urine from morning void preferred.

Collection Medium:

Yellow top round bottom tube (no additive)

Minimum:

Collect 20 mL random urine in THREE yellow top round bottom tubes (no additive).

Absolute Minimum is 10 mL random urine.

Rejection Criteria:

Specimens containing preservatives.

Turn Around Time:

4-14 days upon receipt at reference laboratory

Reference Range:

Electrophoresis Pattern
   By report

Quantitative, Urine
   0-5 months: 14.6-47.8 mg/mmol creatinine
   6-11 months: 3.7-35.5 mg/mmol creatinine
   1-2 years: 5.4-30.8 mg/mmol creatinine
   3-6 years: 5.2-16.7 mg/mmol creatinine
   7-13 years: 2.4-10.2 mg/mmol creatinine
   14 years or older: 0.0-7.1 mg/mmol creatinine

Interpretive Data:

Mucopolysaccharides (Glycosaminoglycans) include: Keratan Sulfate, Heparan Sulfate, Dermatan Sulfate, and Chondroitin Sulfates 4 and 6. The excretion of Heparan Sulfate is variable. A normal mucopoly- saccharides screen does not exclude Sanfilippo Syndrome (Mucopolysaccharidosis Type III).

Comments:

The Patient History for Mucopolysaccharides (MPS) Testing form from ARUP Laboratories needs to be filled out and accompany the sample.

Methodology:

Electrophoresis/Spectrophotometry

CPT Code:

82664, 83864

See Additional Information:
Urine Tests Requiring no Preservatives