Mannose-binding Lectin (MBL)
Order Code: MBL
Epic Lab Code: LAB4490
Order Form: A-1a Miscellaneous Request or Epic Req
Commercial Mail-out Laboratory
6240 RCP
356-3527
Specimen:
Serum
Collection Medium:
Red top tube
Minimum:
Preferred minimum: 1 mL serum Absolute minimum: 0.3 mL serum
Rejection Criteria:
No hemolysis, lipemia, gels or glass tubes.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection.
Specimen Instructions:
Do not submit specimens that have been heat treated. Do not submit the sample in a glass tube. Overnight fasting is preferred.
Analytic Time:
within 10 days upon receipt at reference laboratory
Reference Range:
Mannose-binding Lectin ng/mL DEFICIENT: <100 NORMAL: >=100 Mannan-binding lectin (MBL) is a plasma collection (c-type lectin) and is considered an important component of the innate immune system. Clinical studies have used 50 or 100 ng/mL to define severe MBL deficiency. MBL is also known to activate the classical complement pathway through its binding to serine proteases MASP-2 and MASP-1. MBL deficiency has been associated with recurrent infections in children 6 months to 17 months of age, during the time when the adaptive immune system (IgG Production) is not fully mature.
Methodology:
Enzyme Linked Immunosorbent Immunoassay
CPT Code:
83520