Specimen:

Serum

Collection Medium:

Minimum:

Adult preferred minimum:  1 mL serum
Adult absolute minimum:  0.5 mL serum
Pediatric minimum:  0.2 mL serum

Rejection Criteria:

Hemolyzed, lipemic, contaminated, or heat-inactivated specimens.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection.

Analytic Time:

5 days upon receipt at reference laboratory

Reference Range:

0.0-20.0 U: Negative
20.1-24.9 U: Equivocal
Greater than or equal to 25.0 U: Positive

Interpretive Data:

The presence of SLA antibodies has almost 100% specificity for 
autoimmune hepatitis, although only 12-30% have these antibodies.  
Thus, a negative SLA IgG test does not rule out autoimmune hepatitis.

Methodology:

Enzyme-Linked Immunosorbent Assay

CPT Code:

83516