Sirolimus
Order Code: SIR
Epic Lab Code: LAB898
Order Form: A-1a Therapeutic Drug Analysis or Epic Req
Chemistry
6240 RCP
356-3527
Specimen:
Whole Blood
Collection Medium:
Lavender top tube 3 mL (EDTA)
Minimum:
2/3 full in lavender top (EDTA) tube or ONE lavender top (EDTA) microtube for pediatric patients.
Testing Schedule:
Batch analysis performed on Tuesdays and Fridays. Sample must be received by 0900 for same day service. For additional services, contact Clinical Pathology Resident on-call at pager #3404.
Reference Range:
5-20 ng/mL
Comments:
Everolimus (Zortress®, Afinitor®) cross-reacts significantly with the sirolimus immunoassay. Sirolimus blood concentrations cannot be determined reliably in patients whose blood has both sirolimus and everolimus. This can occur when patients are being transitioned from sirolimus to everolimus or everolimus to sirolimus.
Methodology:
Chemiluminescent Microparticle Immunoassay
CPT Code:
80195