The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK

Perforin Granzyme
Order Code: PERGRA
Order Form: A-1a Miscellaneous Request or IPR Req 		  Commercial "Mail-out" Laboratory
6240 RCP
356-3527 
Specimen
 
Whole blood
Collection Medium:
Green top tube (Na Heparin) 


Minimum:


Note: Results from same day CBC must be included.

Ship Monday through Thursday only, no weekend delivery.  Must reach 
reference laboratory within 24 hours of collection.

Preferred minimum: 10 mL whole blood, green top (Na Heparin) tube
Absolute minimum: 4 mL whole blood, green top (Na Heparin) tube


Analytic Time:


1 week


Comments:


Determines the presence of intracellular perforin, granzyme A, and 
granzyme B expression within cytoxic lymphocytes and/or natural killer 
cell populations.  Deficient expression is associated with a number of 
human diseases, such as hemophagocytic lymphohistiocytosis.


CPT Code:


86359, 86360, 86355, 86357, 88184, 88185 (x5), 88187




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Updated: 08/11/2008

Note: The information contained in this handbook is  
            for use by personnel of University of Iowa Health Care. 
            No other use is implied or intended.