Varicella-Zoster Virus Antibody, IgM by ELISA
Order Code: VZMCSF
Epic Lab Code: LAB4229
Order Form: A-1a Miscellaneous Request or Epic Req
Commercial Mail-out Laboratory
6240 RCP
356-3527
Specimen:
CSF
Collection Medium:
CSF container
Minimum:
Preferred minimum: 0.5 mL Absolute minimum: 0.3 mL
Rejection Criteria:
Heat-inactivated or contaminated specimens; specimens other than CSF
Analytic Time:
1 week upon receipt at reference laboratory
Reference Range:
0.90 ISR or less: Negative - No significant level of IgM antibody to varicella-zoster virus detected. 0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful. 1.10 ISR or greater: Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
Test Limitations:
The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.
Methodology:
Enzyme-Linked Immunosorbent Assay
CPT Code:
86787