The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Canavan Disease, Mutation Analysis
Order Code: CAN
Order Form: A-1a Miscellaneous Request or IPR Req
  Commercial "Mail-out" Laboratory
6240 RCP
356-3527
Specimen
Various
Collection Medium:
Yellow top tube (ACD solution A)
Minimum:
Specimen must arrive at reference laboratory within 96 hours of 
collection.

Submit only 1 of the following specimens:

Blood - Draw blood in a yellow-top (ACD) tube(s), and send 6.0 mL of 
ACD whole blood in original VACUTAINER(S). Invert several times to mix 
blood. Forward unprocessed whole blood promptly at ambient temperature.  
(Absolute Minimum:  0.5 mL)

PLEASE CONTACT LABORATORY REGARDING THE FOLLOWING SPECIMENS
Prenatal Specimens - All prenatal specimens must be accompanied by a 
maternal blood specimen.

Amniotic Fluid
Obtain 20 mL of amniotic fluid. Transfer specimen to 2 screw-capped, 
sterile centrifuge tubes. Send specimen refrigerated.  Specimen cannot 
be frozen.  (Absolute Minimum:  10 mL)

Chorionic Villus
Obtain 20 mg of chorionic villus specimen. Send specimen refrigerated 
in transport media in 15-mL centrifuge tube.  Specimen cannot be 
frozen.  (Absolute Minimum:  5 mL)
Analytic Time:
2 weeks
Reference Range:
An interpretive report, which will include a risk analysis (probability 
of being a carrier), will be provided.
Comments:
Specimen must arrive at reference laboratory within 96 hours of 
collection.
Methodology:
Polymerase Chain Reaction (PCR) with Luminex Technology
CPT Code:
83890, 83896(x5), 83900, 83912, 83914

Alphabetic main page

Updated: 05/15/2007

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.