Specimen

Fibroblasts or Skin Biopsy

Collection Medium:

Minimum:

Fibroblasts: TWO T-25 flasks filled to neck with culture media

Skin biopsy: 4-mm punch, submitted to Cytogenetics Laboratory for 
Fibroblast growth. Fibroblasts are submitted then to the reference 
laboratory.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after
collection period is completed.

Analytic Time:

2 weeks

Reference Range:

Reference Values:
C2       0.29 - 7.46 umol/g protein

C3             <1.15 umol/g protein

C4             <1.60 umol/g protein

C5             <1.02 umol/g protein

C6             <0.69 umol/g protein

C8             <0.72 umol/g protein

C5-DC          <=0.05 umol/g protein

C10:1          <=0.04 umol/g protein

C10            <0.78 umol/g protein

C12            <0.40 umol/g protein

C12-OH         <=0.03 umol/g protein

C14:1          <0.11 umol/g protein

C14            <0.21 umol/g protein

C14:1-OH       <=0.01 umol/g protein

C14-OH         <=0.01 umol/g protein

C16            <1.02 umol/g protein

C16:1-OH       <=0.04 umol/g protein

C16-OH         <=0.03 umol/g protein

Test
Limitations:

No formalin or preservatives

Methodology:

Fibroblasts incubated with Enriched Medium followed by Tandem Mass 
Spectrometry (MS-MS) for Acylcarnitines

CPT Code:

82017, 80500

See also:
Fatty Acid Profile, Comprehensive (C8-C26), Serum