Myelin Associated Glycoprotein (MAG) Antibody, IgM, Serum

Myelin Associated Glycoprotein (MAG) Antibody, IgM

Order Code:	MAG
Epic Lab Code:	LAB3533
Order Form:	A-1a Miscellaneous Request or Epic Req

Commercial Mail-out Laboratory
6240 RCP
356-3527

Specimen:

Serum

Collection Medium:

Red top tube

Minimum:

Preferred Minimum: 1.0 mL serum Absolute Minimum: 0.1 mL serum

Rejection Criteria:

Hemolyzed, severely lipemic specimens, heat activated, contaminated specimens

Testing Schedule:

Weekly

Analytic Time:

4 working days upon receipt at reference laboratory

Reference Range:

Reference Interval: Less than 1000 Titer Units (TU)

Interpretive Data:

Detection of IgM autoantibody against myelin associated glycoprotein (MAG) suggests active demyelination in peripheral neuropathy. The possiblity of MAG antibody involvement in a suspected neuropathy may essentially be ruled out if a MAG IgM negative result is obtained. Detection of MAG IgM antibody by ELISA using human MAG (100 kD) antigen is significantly more sensitive and specific than MAG Western blot and IFA assays using primate antigen.

Methodology:

Enzyme-Linked Immunosorbent Assay (ELISA)

CPT Code:

83516