Adult Minimum: 1.0 mL serum Absolute Adult/Pediatric Minimum: 0.1 mL serum

Adenovirus Antibody, IgG Negative: 0.89 IV or less No significant level of adenovirus IgG antibody detected. Equivocal: 0.90 - 1.10 IV Questionable presence of adenovirus IgG antibody detected. Repeat testing in 10-14 days may be helpful. Positive: 1.11 IV or greater IgG antibodies to adenovirus detected, which may suggest current or past infection. Adenovirus Antibody, IgM Negative: 0.89 IV or less No significant level of adenovirus IgM antibody detected. Equivocal: 0.90 - 1.10 IV Questionable presence of adenovirus IgM antibody detected. Repeat testing in 10-14 days may be helpful. Positive: 1.11 IV or greater IgM antibodies to adenovirus detected, which may suggest current or recent infection.

Adenoviruses are DNA viruses responsible for 4-5 percent of all respiratory illnesses. There are 41 known serotypes with diverse clinical manifestations, ranging from acute pharyngoconjunctival fever and acute respiratory outbreaks to epidemic keratoconjunctivitis and intestinal tract infections. Because of the varied serotypes, adenoviruses cause infections year-round. Although adenovirus infections are rarely fatal, about 50 percent of infants and young children have prolonged intermittent disease and fatal adenovirus infections can occur in infants and immunocompromised adults. Most cases are diagnosed on clinical grounds alone. Viral culture can be used in selected clinical settings. Serologic testing usually relies upon the demonstration of antibodies to group-specific antigens. Individual serotype specificity is seldom required.