Specimen

Plasma

Collection Medium:

Minimum:

Adult Preferred Minimum:  2.0 mL
Adult Absolute Minimum: 1.2 mL
Pediatric Minimum 0.6 mL

Rejection Criteria:

Serum, specimens collected in heparin, citrate or oxalate tubes, 
refrigerated specimens, or hemolyzed specimens.

Delivery Instructions:

Deliver to laboratory immediately after collection.  Critical frozen.

Analytic Time:

2 working days (upon receipt)

Reference Range:

Adult, normal sodium diet:
  Supine: 0.2-1.6 ng/mL/hr
  Upright: 0.5-4.0 ng/mL/hr
Newborn (1-7 days): 2.0-35.0 ng/mL/hr
Cord blood: 4.0-32.0 ng/mL/hr
Children, normal sodium diet, supine:
  1-12 months: 2.4-37.0 ng/mL/hr
  13 months-3 years: 1.7-11.2 ng/mL/hr
  4-5 years: 1.0-6.5 ng/mL/hr
  6-10 years: 0.5-5.9 ng/mL/hr
  11-15 years: 0.5-3.3 ng/mL/hr

Comments:

Plasma renin activity measures enzyme ability to convert 
angiotensinogen to angiotensen 1 and is limited by the availability of 
angiotensinogen.  Plasma renin activity is not an accurate indicator of 
enzyme activity when angiotensinogen is decreased.

Test
Limitations:

If an upright sample is collected, patient should be upright (seated or 
standing) for at least two hours.
Do not refrigerate. Do not collect in refrigerated tubes.

Methodology:

Radioimmunoassay

CPT Code:

84244