Copper
Order Code: CULT
Epic Lab Code: LAB2920
Order Form: A-1a Miscellaneous Request or Epic Req
Commercial Mail-out Laboratory
01250 PFP
356-3527
Specimen:
Liver Tissue
Collection Medium:
Miscellaneous container; contact laboratory
Minimum:
At least a 1 cm long specimen (obtained with an 18 gauge needle) at 2- 8°C. Tissue can be fresh, paraffin-embedded, formalin-fixed, or dried. Specimens other than paraffin-embedded should be stored and transported in a metal-free container such as a royal blue (no additive).
Rejection Criteria:
Specimens less than 0.25 mg will be rejected. Paraffin blocks that have been processed with Hollande's stain will be rejected.
Turn Around Time:
1 week upon receipt at reference laboratory
Reference Range:
15 - 55 ug/g liver tissue
Interpretive Data:
Hepatic copper concentrations approach or exceed 250 ug/g in untreated Wilson's disease. Elevated hepatic copper is also seen with chronic biliary obstruction and cholestatic conditions. Results inconsistent with other findings may reflect heterogeneity in hepatic copper distribution.
Comments:
Submit specimen to Surgical Pathology at 5804 JPP.
Methodology:
Inductively Coupled Plasma/Mass Spectrometry
CPT Code:
82525