Imuran (6MP/6TG Thiopurine therapy)
| Order Code: | PROIM |
| Epic Lab Code: | LAB3909 |
| Order Form: | A-1a Miscellaneous Request or Epic Req |
Commercial Mail-out Laboratory
6240 RCP
356-3527
6240 RCP
356-3527
Specimen:
Whole Blood
Collection Medium:
 | and | |
| Lavender top tube 3 mL (EDTA) | Lavender top tube 3 mL (EDTA) |
Minimum:
5 mL EDTA whole blood
Analytic Time:
5 days upon receipt at reference laboratory
Reference Range:
Therapeutic Range - 6-TGN: 235-400 pmole/8x108 RBC; 6-MMPN:
<5,700 pmole/8x108 RBC.
Routine monitoring of WBC and liver enzymes must be continued to assure optimized response while minimizing risk of leukopenia and drug-induced hepatotoxicity. The target therapeutic range and target toxic thresholds were established in an IBD patient population receiving 6-mercaptopurine or azathioprine.
Routine monitoring of WBC and liver enzymes must be continued to assure optimized response while minimizing risk of leukopenia and drug-induced hepatotoxicity. The target therapeutic range and target toxic thresholds were established in an IBD patient population receiving 6-mercaptopurine or azathioprine.
Comments:
If specimen is refrigerated, specimen can be stored for seven days.
Record the following items on the requisition:
Date of Birth
Gender
Ordering Doctor's Name
Test
Limitations:
Test provides quantitative measurement of response/toxicity of 6MP.
Collect specimen three weeks after beginning the therapy or after dose
adjustment.
Methodology:
High Pressure Liquid Chromatography
CPT Code:
82491(x2)