Endomysial IgA Antibody Screen with Reflex Titer and Interpretation
| Order Code: | EMAIGA |
| Epic Lab Code: | LAB1301 |
| Order Form: | A-1a Immunopathology or Epic Req |
Immunopathology
5238 RCP
356-2688
5238 RCP
356-2688
Specimen:
Serum
Collection Medium:
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| Red top tube |
Minimum:
Adult - 5 mL; red top tube
Pediatric - 2 mL; red top tube
Pediatric - 2 mL; red top tube
Testing Schedule:
Bi-weekly (Mon and Thurs) - Batch analysis performed
twice weekly on Mondays and Thursdays excluding
university holidays.
Analytic Time:
1 week
Reference Range:
< 1:5 Titer
Endomysial IgA antibody is detected in 70-76% of patients with
dermatitis herpetiformis and 90+% of patients with celiac
disease who are on a gluten-containing diet. Occurence of endomysial
IgA antibody decreases significantly on gluten-free diets. Note:
Selective IgA deficiencies affect 3-5% of celiac and dermatitis
herpetiformis patients and this condition will cause a "false negative"
test. If IgA deficiency is known, please note requisition and IgG
anti-EMA test will be done instead of IgA.
Comments:
Include relevant clinical information and consultation request.
Methodology:
Indirect Immunofluorescence
CPT Code:
86255 Endomysial Antibody IgA screen
86255-26 Endomysial Antibody IgA screen interpretation
86256 Endomysial Antibody IgA titer
86256-26 Endomysial Antibody IgA titer interpretation
