The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Drugs of Abuse Screen
Order Code: DAUPOC
Order Form: A-1a Miscellaneous Request or IPR Req
  Hematology
6240 RCP
356-3527
Specimen
Urine
Collection Medium:
Urine - Random urine container
Minimum:
10 mls random urine
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Analytic Time:
2 hours (upon receipt in laboratory)
Reference Range:
None
Comments:
Screen includes amphetamines, methamphetamines, barbiturates, 
benzodiazepines, cocaine, phencyclidine, opiates, 
tetrahydrocannabinoids (THC) and urinary tricyclic antidepressants.
A positive result for any of the tested drugs indicates the presence of 
the drug or metabolites in the urine, but does not measure the level of 
intoxication.

If confirmation is needed for amphetamines, methamphetamines, 
barbiturates, benzodiazepines, cocaine,  phencyclidine, opiates, and 
tetrahydrocannabinoids (THC), call the Laboratory 356-3527.  Allow up 
to seven days for confirmatory results.  Confirmation is at an 
additional charge.

Suggested confirmation of urinary tricyclic antidepressants is by the 
serum tricyclic antidepresssant screen test performed by Clinical 
Chemistry.  See additional confirmation information at the links below.

Test Cut-off Concentrations (ng/ml)
Amphetamines                  1000
Methamphetamines              1000
Barbiturates                   300
Benzodiazepine                 300
Cocaine                        300
Opiate                         300
Phencyclidine                   25
Tricyclic antidepressants     1000
THC                             50

References:

Belson MG, Simon HK, Sullivan K, Geller RJ.  The Utility of Toxicologic 
Analysis in Children with Suspected Ingestion.  Pediatr Emerg Care 
1999;15:383-387.

Bast RP, Helmer SD, Henderson SR, Rogers MA, Shapiro WM, Smith RS.  
Limited Utility of Routine Drug Screening in Trauma Patients.  South 
Med J 2000;93:397-399.

De La Torre R, Domino-Salvany A, Badia R, Gonzalez G, McFarlane D, San 
L, Torrens M.  Clinical Evaluation of the Triage Analytical Device for 
Drugs-of-Abuse Testing.  Clinical Chemistry 1996;42(9):1433-1438.

Hammett-Stabler CA, Pesce AJ, Cannon DJ.  Urine Drug Screening in the 
Medical Setting.  Clinica Chimica Acta 2002;315:125-135.

Schiller MJ, Shumway M, Batki SL.  Utility of Routine Drug Screening in 
a Psychiatric Emergency Setting.  Psychiatric Services 2000;51:474-478.

Sugarman JM, Rodgers GC, Paul RI.  Utility of Toxicology Screening in a 
Pediatric Emergency Department.  Pediatric Emergency Care.  Pediatric 
Emergency Care 1997;13(3):194-197.
Test
Limitations:
There is the possibility that other substances and/or factors may 
interfere with the test and cause erroneous results (e.g., technical or 
procedural errors).  Call the lab at 319-356-3527 for additional 
information.  See appendix "Cross Reacting Drugs".
Methodology:
Triage TOX Drug screen is a competitive fluorescence immunoassay used 
for the qualitative determination of nine common drugs of abuse in 
urine specimens.
CPT Code:
80101 x9
 
See also:
Barbiturate Confirmation, Urine
Benzodiazepine Confirmation, Urine
Cocaine Confirmation, Urine
Drugs of Abuse Screen Confirmation, Urine
Opiate Confirmation, Urine
Phencyclidine (PCP), Confirmation, Quantitative, Urine
THC Confirmation, Urine
Tricyclic Antidepressant Toxicology Screen (TCA), Serum
 
See Additional Information:
Cross Reacting Drugs

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Updated: 02/13/2007

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.