Thyroid Stimulating Immunoglobulin
| Order Code: | TSI |
| Epic Lab Code: | LAB4165 |
| Order Form: | A-1a Miscellaneous Request or Epic Req |
Commercial Mail-out Laboratory
01250 PFP
356-3527
01250 PFP
356-3527
Specimen:
Serum
Collection Medium:
 |
| Red top tube |
Minimum:
Preferred Minimum: 1.0 mL serum
Absolute Minimum: 0.7 mL serum
Absolute Minimum: 0.7 mL serum
Rejection Criteria:
Plasma
Turn Around
Time:
2-5 days upon receipt at reference laboratory
Reference Range:
Negative - 110% basal activity or less
Positive - 111% basal activity or greater
Positive - 111% basal activity or greater
Interpretive Data:
Positive results (111 percent or greater) are consistent with Graves
disease but do not always correlate with the presence and severity of
hyperthyroidism. Antibodies to the Thyroid Stimulating Hormone Receptor
(TSHR) may be stimulating, blocking, or neutral. Stimulating antibodies
mimic the action of TSH and cause hyperthyroidism (Graves disease).
This test determines the net effect of all TSHR antibody types present
in the serum specimen.
Note: An elevated Thyroid Stimulating Hormone (TSH) value above 76 mU/L may produce a weakly positive Thyroid Stimulating Immunoglobulin (TSI) result (111 percent or greater).
Note: An elevated Thyroid Stimulating Hormone (TSH) value above 76 mU/L may produce a weakly positive Thyroid Stimulating Immunoglobulin (TSI) result (111 percent or greater).
Comments:
For any results 130% and above, the following statement will be
added: "An elevated TSH value above 10 mIU/L may produce a low positive
result."
Methodology:
Quantitative Bioassay/Quantitative Chemiluminescence
CPT Code:
84445