Specimen:

Tissue or FNA

Testing Schedule:

0800-1630 Monday through Friday.  For additional services, 
contact Clinical Pathology Resident on-call at pager #3404.

Analytic Time:

2 days

Reference Range:

The pathologist will provide an interpretative report.

Comments:

Please send a Surgical Pathology H-1 form to Immunopathology with this 
request.

If PR studies are desired on previous surgical material, please contact 
the Immunopathology resident at #4514. Provide the patient's name, 
hospital number and surgical pathology specimen number.Please send a 
Surgical Pathology H-1 form to Immunopathology with this request.

Progesterone Receptor (PR) expression in breast carcinomas, similar to 
estrogen receptor positivity, has been associated with tumor 
responsiveness to hormonal therapy. Immunohistochemical (IHC) staining 
of formalin-fixed, paraffin-embedded tumor sections has proven to be a 
sensitive means of defining positivity. An immunohistochemical score is 
generated by the interpreting pathologist. A score >2 has been used to 
define PR positivity.

Methodology:

Immunohistochemistry

CPT Code:

88342 (Technical)
88342-26 Professional Interpretation)

See also:
Estrogen Receptor, Tissue or FNA