The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Progesterone Receptor
Order Code: IPRF
Order Form: H-1 Surgical Pathology or IPR Req
  Immunopathology
5238 RCP
356-2688
Specimen
Tissue or FNA
Testing Schedule:
0800-1630 Monday through Friday.  For additional services, 
contact Clinical Pathology Resident on-call at pager #3404.
Analytic Time:
2 days
Reference Range:
The pathologist will provide an interpretative report.
Comments:
Please send a Surgical Pathology H-1 form to Immunopathology with this 
request.

If PR studies are desired on previous surgical material, please contact 
the Immunopathology resident at #4514. Provide the patient's name, 
hospital number and surgical pathology specimen number.Please send a 
Surgical Pathology H-1 form to Immunopathology with this request.

Progesterone Receptor (PR) expression in breast carcinomas, similar to 
estrogen receptor positivity, has been associated with tumor 
responsiveness to hormonal therapy. Immunohistochemical (IHC) staining 
of formalin-fixed, paraffin-embedded tumor sections has proven to be a 
sensitive means of defining positivity. An immunohistochemical score is 
generated by the interpreting pathologist. A score >2 has been used to 
define PR positivity.
Methodology:
Immunohistochemistry
CPT Code:
88342 (Technical)
88342-26 Professional Interpretation)
 
See also:
Estrogen Receptor, Tissue or FNA

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Updated: 02/15/2007

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.