The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK

Lamotrigine (Lamictal)
Order Code: LAMT
Order Form: A-1a Miscellaneous Request or IPR Req 		  Commercial "Mail-out" Laboratory
6240 RCP
356-3527 
Specimen
 
Serum
Collection Medium:
Red top tube 


Alternate
Collection Media:


Green top tube (Na Heparin), Lavender top tube (EDTA)


Minimum:


0.6 mL serum, heparinized plasma or EDTA plasma


Rejection Criteria:


Gel separator tubes


Analytic Time:


4 days


Reference Range:


Therapeutic range not well established.


Test
Limitations:


The proposed therapeutic range for seizure control is 3 - 14 ug/ml.  
Concentrations that exceed 15 ug/ml may contribute to adverse effects.  
Pharmacokinetics varies widely, particularly with co-medications and/or 
compromised renal function.


Methodology:


High Performance Liquid Chromatography (HPLC)


CPT Code:


82486




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Updated: 05/22/2007

Note: The information contained in this handbook is  
            for use by personnel of University of Iowa Health Care. 
            No other use is implied or intended.