Mercury
| Label Mnemonic: | HGU |
| Epic code: | LAB408 |
| Downtime form: | A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Urine More information
Specimen
Instructions:
Refrigerate during collection in plastic container. Studies indicate
that refrigeration of urine alone, during and after collection,
preserves specimens adequately, if tested within 14 days of
collection.
Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non- essential over-the-counter medications (upon the advice of their physician), and avoid shellfish and seafood for 48 to 72 hours. High concentrations of iodine may interfere with elemental testing. Collection of urine specimens from patients receiving iodinated or gadolinium-based contrast media should be avoided for a minimum of 72 hours post-exposure. Collection from patients with impaired kidney function should be avoided for a minimum of 14 days postcontrast media exposure.
Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non- essential over-the-counter medications (upon the advice of their physician), and avoid shellfish and seafood for 48 to 72 hours. High concentrations of iodine may interfere with elemental testing. Collection of urine specimens from patients receiving iodinated or gadolinium-based contrast media should be avoided for a minimum of 72 hours post-exposure. Collection from patients with impaired kidney function should be avoided for a minimum of 14 days postcontrast media exposure.
Collection Medium:
) |
| Urine - 24 hour/timed plastic urine container |
Minimum:
Preferred Minimum: 8 mL aliquot from a well-mixed collection from 24
hour collection.
Absolute Minimum: 1 mL aliquot from a well-mixed collection from 24 hour collection.
Refrigerate during collection and submission.
Absolute Minimum: 1 mL aliquot from a well-mixed collection from 24 hour collection.
Refrigerate during collection and submission.
Rejection Criteria:
Urine collected within 72 hours after administration of iodinated or
gadolinium-based contrast media. Acid preserved urine. Specimens
contaminated with blood or fecal material. Specimens transported in
non-trace element free transport tube (with the exception of the
original device).
Turn Around
Time:
1-5 days upon receipt at reference laboratory
Reference Range:
COMPONENTS REFERENCE INTERVAL
Mercury, Urine-per volume 0.0-5.0 μg/d
Mercury, Urine-per 24h 0.0-20.0 μg/L
Mercury, Urine-ratio to CRT 0.0-20.0 μg/gCRT
Creatinine, Urine-per 24h mg/d Male Female
3-8 yrs: 140-700 3-8 yrs: 140-700
9-12 yrs: 300-1300 9-12 yrs: 300-1300
13-17 yrs: 500-2300 13-17 yrs: 400-1600
18-50 yrs: 1000-2500 18-50 yrs: 700-1600
51-80 yrs: 800-2100 51-80 yrs: 500-1400
81 yrs+: 600-2000 81 yrs+: 400-1300
Interpretive Data:
Urinary mercury levels predominantly reflect acute or chronic
elemental or inorganic mercury exposure. Urine concentrations in
unexposed individuals are typically less than 10 μg/L. 24 hour urine concentrations of 30 to 100 μg/L may be associated with subclinical neuropsychiatric symptoms and tremor while concentrations greater than 100 μg/L can be associated with overt neuropsychiatric disturbances and tremors. Urine mercury levels may be useful in monitoring chelation therapy.
Comments:
Record total volume and collection time interval on transport tube and
on test request form.
Stability: Mercury is volatile; concentration may decrease over time.
Stability: Mercury is volatile; concentration may decrease over time.
Methodology:
Quantitative Inductively Coupled Plasma-Mass Spectrometry
CPT Code:
83825