Iron
| Order Code: | FET |
| Epic Lab Code: | LAB3444 |
| Order Form: | A-1a Miscellaneous Request or Epic Req |
Commercial Mail-out Laboratory
6240 RCP
356-3527
6240 RCP
356-3527
Specimen:
Liver Tissue
Collection Medium:
| Miscellaneous container; contact laboratory |
Minimum:
1 cm long specimen obtained with an 18 gauge needle. Tissue can be
fresh, paraffin-embedded, formalin-fixed, or dried. Formalin is
acceptable, but not preferred. Paraffin blocks are acceptable.
Metal-free vial available from Specimen Control, 6240 RCP.
Rejection Criteria:
Specimens less than 0.25 mg dry weight. Samples stored or shipped in
saline.
Analytic Time:
2-6 days upon receipt at reference laboratory
Reference Range:
Male:
Hepatic Iron Content (HIC): 200 - 2,000 μg/g of tissue
Hepatic Iron Index (HII): Less than 1.0
Female:
Hepatic Iron Content (HIC): 200 - 1,600 μg/g of tissue
Hepatic Iron Index (HII): Less than 1.0
Interpretive Data:
A Hepatic Iron Index (HII) is not calculated for patients less than 14
years. An HII less than 1.0 is consistent with normal iron
accumulation. An HII 1.0 through 1.9 is consistent with mild iron
accumulation such as in heterozygous hemochromatosis or alcoholic liver
disease. An HII greater than 1.9 is consistent with iron overload such
as in homozygous hemochromatosis, multiple transfusions, porphyria
cutanea tarda, and cirrhotic liver disease. The HII will decrease with
chronic blood loss or phlebotomy.
Comments:
Submit to Surgical Pathology 5804 JPP. Iron on Liver Tissue will be
ordered if applicable by Pathologist review.
Record age on test requisition in order to calculate iron index.
Methodology:
Inductively Coupled Plasma/Mass Spectrometry
CPT Code:
83789