The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Parvovirus B19 Antibodies, IgG & IgM
Order Code: PARVO
Order Form: A-1a Miscellaneous Request or IPR Req
  Commercial "Mail-out" Laboratory
6240 RCP
356-3527
Specimen
Serum
Collection Medium:
Red top tube
Alternate
Collection Media:
Lavender top tube (EDTA), Green top tube (Na Heparin), Light Green top 
tube (Lithium Heparin)
Minimum:
Preferred adult minimum: 0.5 mL serum
Absolute adult minimum: 0.2 mL serum
Pediatric minimum: 0.1 mL serum
Rejection Criteria:
Lipemic or icteric specimens.
Analytic Time:
1 week
Reference Range:
Parvovirus B19 IgG Index
  IV = Index Value
0.89 IV or less:  Negative -  No significant level of detectable
                              Parvovirus B19 IgG antibody
0.90 - 1.10 IV:  Equivocal - Repeat testing in 10-14 days may be
                             helpful
1.11 IV or greater:  Positive -  IgG antibody to Parvovirus B19
                                 detected, which may indicate a
                                 current or past infection.

Parvovirus B19 IgM Index
   IV = Index Value
0.89 IV or less:  Negative -  No significant level of detectable
                              Parvovirus B19 IgM antibody
0.90 - 1.10 IV:  Equivocal - Repeat testing in 10-14 days may be
                             helpful
1.11 IV or greater:  Positive -  IgM antibody to Parvovirus B19
                                 detected, which may indicate a
                                 current or recent infection.
                                 However, low levels of IgM antibodies
                                 may occasionally persist for more
                                 than 12 months post-infection.
Comments:
Mark specimens as "acute" or "convalescent" specimen.  Parallel testing 
is preferred and convalescent samples must be received within 30 days 
from receipt of acute samples.
Methodology:
Enzyme Linked Immunosorbent Assay
CPT Code:
86747(x2)
 
See also:
Parvovirus, PCR, Human, Serum, Plasma, Amniotic or Synovial Fluid

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Updated: 05/23/2007

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.