Alpha Fetoprotein

Label Mnemonic:	AFP
Epic code:	LAB554
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Chemistry
6240 RCP
356-3527

Specimen(s):

Plasma

Collection Medium:

Plasma Separator Tube 4.5 mL

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3 mL whole blood in light green top tube or TWO Microtainer^® devices for pediatric patients.

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Turn Around Time:

1 hour (upon receipt in laboratory)

Reference Range:

                             All units in ng/mL
Age                     Male                   Female
------                  -------------          ------------
0-13 days               5,000 - 105,000        5,000 - 105,000
14-30 days              300 - 60,000           300 - 60,000
1 month                 100 - 10,000           100 - 10,000
2 months                40 - 1,000             40 - 1,000
3 months                11 - 300               11 - 300
4 months                5 - 200                5 - 200
5 months                0 - 90                 0 - 90
6-11 months             0 - 60                 0 - 97
1 year                  0 - 17                 0 - 41
2 years                 0 - 12                 0 - 12
3+ years                0 - 9                  0 - 9

Reference ranges updated 6/30/2011 by addition of pediatric reference 
ranges below 3 years old.

Comments:

This result was obtained using the Roche Diagnostics electrochemiluminescence immunoassay on a Roche Cobas analyzer. Patient results determined by different assay manufacturers or methods are not interchangeable.

Assay updated with increased tolerance to biotin on March 5, 2024.

Test Limitations:

Assay is unaffected by icterus (<65 mg/dL), hemolysis (Hb <2200 mg/dL), lipemia (triglycerides <1500 mg/dL), and biotin (<1200 ng/mL).

Methodology:

Electrochemiluminescence Immunoassay

CPT Code:

82105