MADS+: discovery of differential splicing events from Affymetrix exon junction array data

Cassette Exon is the inclusion or skipping of a single exon in the isoforms.

HJAY_Plot_cassette.pdf contains the graphs of alternatively spliced cassette exons. The red lines in the figure represent the gene expression indexes. The blue lines in the figure represent the probe intensities.

 

 

For cassette exons, up=upstream 'include' exon-exon junction probeset, down=downstream 'include' exon-exon junction, exon=exon probeset and skip='skip' exon-exon junction. The numbers below the names are the p values for each probeset with directions. Positive p values indicate more inclusion levels in second group of samples. Negative p values indicate less inclusion levels in second group of samples. 

 

HJAY_excel_cassette.txt contains the gene names, coordinates and p values.

HJAY_gene_ID HJAY_cluster_ID Gene_symbol Upstream_junction_ID [p value, direction] Downstream_junction_ID [p value, direction] Skip_junction_ID [p value, direction] Exon_ID [p value, direction] Gene_symbol HJAY_exon_ID Exon_chromosome Exon_strand Exon_start Exon_stop
818860 TC1000560 SLK JUC1000041938 [1.2410397058100001e-08, '+'] JUC1000042004 [1.1255700314199999e-26, '+'] JUC1000041899 [5.40871536197e-09, '-'] PSR100005227 [2.4307432163599999e-23, '+'] SLK 131337 chr10 + 105760564 105760656