Xuebo Liu, Ph.D.
Associate Research Scientist
Publications (from Sigmund Lab):
Keen HL, Halabi CM, Beyer AM, de Lange WJ, Liu X, Maeda N, Faraci FM, Casavant TL, Sigmund CD.
Arterioscler Thromb Vasc Biol. 2009 Dec 17. [Epub ahead of print]
PMID: 20018933
Regulation of renin gene expression by oxidative stress.
Itani H, Liu X, Sarsour EH, Goswami PC, Born E, Keen HL, Sigmund CD.
Hypertension. 2009;53:1070-1076.
PMID: 19433777
Upstream Stimulatory Factor Is Required for Human Angiotensinogen Expression and Differential Regulation by the A-20C Polymorphism.
Circulation Research. 2008; 103: 940-947.
PMID: 18802024 [PubMed - as supplied by publisher]
Dysregulated Human Renin Expression in Transgenic Mice Carrying Truncated Genomic Constructs: Evidence Supporting the Presence of Insulators at the Renin Locus.
Am J Physiol Renal Physiol. 2008 Jul 16. [Epub ahead of print]
PMID: 18632798 [PubMed - as supplied by publisher]
Functional characterization of polymorphisms in the kidney enhancer of the human renin gene.
Endocrinology. 2007 Mar;148(3):1424-30. Epub 2006 Dec 7.
PMID: 17158202 [PubMed - indexed for MEDLINE]
Interleukin-1beta attenuates renin gene expression via a mitogen-activated protein kinase kinase-extracellular signal-regulated kinase and signal transducer and activator of transcription 3-dependent mechanism in As4.1 cells.
Endocrinology. 2006 Dec;147(12):6011-8. Epub 2006 Sep 7.
PMID: 16959849 [PubMed - indexed for MEDLINE]
Evidence supporting a functional role for intracellular renin in the brain.
Hypertension. 2006 Mar;47(3):461-6. Epub 2006 Jan 30.
PMID: 16446393 [PubMed - indexed for MEDLINE]
Nuclear localization of angiotensinogen in astrocytes.
Am J Physiol Regul Integr Comp Physiol. 2005 Feb;288(2):R539-46. Epub 2004 Sep 23.
PMID: 15388495 [PubMed - indexed for MEDLINE]
Hypothalamic PI3K and MAPK differentially mediate regional sympathetic activation to insulin.
J Clin Invest. 2004 Sep;114(5):652-8.
PMID: 15343383 [PubMed - indexed for MEDLINE]
Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells.
Circulation. 2004 May 11;109(18):2221-6. Epub 2004 Apr 26.
PMID: 15117840 [PubMed - indexed for MEDLINE]
Identification of a nuclear orphan receptor (Ear2) as a negative regulator of renin gene transcription.
Circ Res. 2003 May 16;92(9):1033-40. Epub 2003 Apr 10.
PMID: 12690040 [PubMed - indexed for MEDLINE]
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