Cytoplasmic expression of mutant gI protein gI-S343A transfected with the plasmid PTM1-gI-S343A. This mutant has a Serine changed to an Alanine at amino acid 343 which lies in a major phosphorylation site. Each of the mutants showed similar cellular distubution as wild type gI. Other experiments showed that the phosphorylation of the mutant gI was signifigantly lowered.

 

 

 

 

Ye M, Duus KM, Peng J, Price DH, Grose C (1999) Varicella-zoster virus Fc receptor component gI is phosphorylated on its endodomain by a cyclin-dependent kinase. J Virol 73(2), 1320-30
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