Publications 2005

Gonzalez-Alegre P, Bode N, Davidson BL, Paulsen HL. Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia. J Neurosci 25 (45): 10502-9, 2005. (Abstract)

Davidson BL, Harper SQ. Viral delivery of recombinant short hairpin RNAs. Methods Enzymol 392:145-173, 2005. (Abstract)

Liu G, Martins IH, Wemmie, JA, Chiorini JA, Davidson BL. Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated type 4 vectors. Gene Ther 12 (25):9321-7, 2005. (Abstract)

Stein CS, Martins I, Davidson BL. The lymphocytic choriomeningitis virus envelope glycoprotein targets lentiviral gene transfer vector to neural progenitors in the murine brain. Mol Ther (3):382-9, 2005. (Abstract)

Harper SQ, Staber PD, He X, Eliason SL, Martins IH, Mao Q, Yang L, Kotin RM, Paulson HL, Davidson BL. RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model. PNAS 102 (16):5820-5825, 2005. (Abstract)

Harper SQ, Davidson BL. Plasmid-based RNA interference: construction of small-hairpin RNA expression vectors. Methods Mol Biol 309:219-236, 2005. (Abstract)

Liu G, Martins IH, Chiorini JA, Davidson BL. Adeno-associated virus type 4 (AAV4) targets ependyma and astrocytes in the subventricular zone and RMS. Gene Ther 12 (20): 1503-8, 2005. (Abstract)

Kang Y, Xie L, Tran DT, Stein CS, Hickey M, Davidson BL, McCray Jr PB. Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer. Blood 1 (106):1552-8 2005. (Abstract)

Miller VM, Nelson RF, Gouvion CM, Williams A, Rodriguez-Lebron E, Harper SQ, Davidson BL, Rebagliati MR, Paulson HL. CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo. J Neurosci 25 (40):9152-9161, 2005. (Abstract)

Law LK, Davidson BL. What does it take to bind CAR? Mol Ther 12 (4):599-609, 2005. (Abstract)

Orii KO, Grubb JH, Vogler C, Levy B, Tan Y, Markova K, Davidson BL, Mao Q, Orii T, Kondo N, Sly WS. Defining the pathway for Tat-mediated delivery of beta-glucuronidase in cultured cells and MPS VII mice. Mol Ther 12 (2):345-352, 2005. (Abstract)

Harper SQ, Davidson BL. Plasmid-based RNA interference: construction of small-hairpin RNA expression vectors. Methods Mol Biol 309:219-235, 2005. (Abstract)

Publications 2004

Xia H, Mao Q, Eliason SL, Harper SQ, Martins IH, Orr HT, Paulson HL, Yang L, Kotin RM, Davidson BL. RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nature Medicine 10(8):775-776, 2004. (Abstract)

Alisky JM, Davidson BL. Towards therapy using RNA interference. Am J Pharmacogenomics 4(1):45-51, 2004. (Abstract)

Davidson BL, Paulson HL. Molecular medicine for the brain: silencing of disease genes with RNA interference. Lancet Neurol 3(3):145-9, 2004. (Abstract)

Alisky JM, Davidson BL. Gene transfer to brain and spinal cord using recombinant adenoviral vectors. Methods Mol Biol 246:91-120, 2004. (Abstract)

Miller VM, Gouvion CM, Davidson BL, Paulson HL. Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles. Nucleic Acids Res 32(2):661-8, 2004. (Abstract)