Publications 2002-present

Zhu, M.N., Ramirez, L.M., Lee, R.L., Pelech, S.L., Magnuson, N.S., Bishop, G.A. and Gold, M.R. CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kB pathway. J. Immunol. 168: 744-754, 2002.

Hostager, B.S. and Bishop, G.A. Role of TRAF2 in the activation of IgM secretion by CD40 and CD120b. J. Immunol. 168:3318-3322, 2002.

Bishop, G.A., Hostager, B.S. and Brown, K.D. Mechanisms of tumor necrosis factor receptor associated factor (TRAF) regulation in B lymphocytes, J. Leuk. Biol. 72:19-23, 2002.

Bishop, G.A. and Busch, L.K. Molecular mechanisms of B lymphocyte transformation by Epstein-Barr virus, Invited review for Microbes & Infection 4:853-857, 2002.

Baccam, M., Woo, S.-Y., Vinson, C. and Bishop, G.A. CD40-mediated transcriptional regulation of the IL-6 gene in B lymphocytes: Involvement of NF-kB, AP-1, and C/EBP. J. Immunol. 170:3099-3108, 2003.

Bishop, G.A. and Hostager, B.S. The CD40-CD154 liaison in B cell-T cell interactions. Invited review for Cytokine and Growth Factor Reviews, 14:297-309, 2003.

Bishop, G.A., Haxhinasto, S., Stunz, L., and Hostager, B.S. Antigen-specific B cell activation. Invited review for CRC Critical Reviews in Immunology 23:149-198, 2003.

Haxhinasto, S.A. and Bishop, G.A. A novel interaction between PKD and TRAFs regulates BCR-CD40 synergy. J. Immunol. 171:4655-4662, 2003.

Bishop, G.A. and Hostager, B.S. TNF-R Family Signaling Complexes. Chapter 56. Invited chapter for Handbook of Cell Signaling, R. Bradshaw and E. Dennis, Eds., Elsevier, Science 2003.

Hostager, B.S., Haxhinasto, S.A., Rowland, S.R. and Bishop, G.A. Novel roles for TRAF2 revealed using TRAF2-deficient B cell lines. J. Biol. Chem. 278:45382-45390, 2003.

Barabanova, Y.A., Kang, H.-K., Myoung, J., Kang, B.S., Bishop, G.A. and Kim, B.S. Role of the MHC class II transmembrane region in antigen presentation and intracellular trafficking. Immunology 111:165-172, 2004.

Haxhinasto, S. and Bishop, G.A. Synergistic B cell activation by CD40 and the B cell antigen receptor: Role of BCR-mediated kinase activation and TRAF regulation. J. Biol. Chem. 279:2575-2582, 2004.

Xie, P., Hostager, B.S. and Bishop, G.A. Requirement for TRAF3 in signaling by LMP1, but not CD40, in B lymphocytes. J. Exp. Med. 199:661-671, 2004.

Stunz, L.L., Busch, L.K., Munroe, M.E., Sigmund, C.D., Tygrett, L.T., Waldschmidt, T.J., and Bishop, G.A. Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture. Immunity 21:255-266, 2004.

Xie, P. and Bishop, G.A. Roles of TRAF3 in signaling by CTAR1 and CTAR2 of LMP1. J. Immunol. 173:5546-5555, 2004.

Bishop, G.A. “The multifaceted roles of TRAFs in the regulation of B lymphocyte function”, invited review for Nature Reviews in Immunology 4:775-786, 2004.

Munroe, M.E. and Bishop, G.A. Role of TRAF2 in distinct and overlapping CD40 and TNFR2/CD120b-mediated B lymphocyte activation. J. Biol. Chem. 279:53222-53231, 2004.

Mukundan, L. Bishop, G.A., Head, K.Z., Zhang, L., Wahl, L.M. and Suttles, J. TRAF6 is an essential mediator of CD40-activated pro-inflammatory pathways in monocytes and macrophages. J. Immunol. 174:1081-1090, 2005.

Bishop, G.A. and Lamb, J.R. Lymphocyte activation: Editorial overview. Curr. Opin. in Immunology (invited editors) 17: 1-3, 2005.

Moore, C.R. and Bishop, G.A. Differential regulation of CD40-mediated TRAF degradation in B lymphocytes. J. Immunol. 175:3780-3789, 2005

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Wu, S., Xie, P., Welsh, K., Li, C., Ni, C., Zhu, X., Reed, J.C., Satterthwait, A.C., Bishop, G.A. and Ely, K.R. LMP1 protein from EBV is a structural decoy in B lymphocytes for binding to TRAF3. J. Biol. Chem. 280:33620-33626, 2005.

Andrade, R.M., Wessendarp, M., Portillo, J.C., Yang, J., Gomez, F.J., Durbin, J.E., Bishop, G.A. and Subuaste, C.S. TRAF6-dependent CD40 signaling primes macrophages to acquire anti-microbial activity in response to TNF-a . J. Immunol. 175:6015-6021, 2005.

Bishop, G.A. CD40 and its viral mimic LMP1. Modern Aspects of Immunobiology 16:6, 2005.

Xie, P., Hostager, B.S., Munroe, M.E., Moore, C.R. and Bishop, G.A. Cooperation between TRAFs 1 and 2 in CD40 signaling. J. Immunol. 176:5388-5400, 2006.

Benson, R., Hostager, B.S. and Bishop, G.A. Rapid CD40-mediated rescue from CD95-induced apoptosis requires TRAF6 and PI3K. Eur. J. Immunol. 36:2535-2543, 2006.

Bishop, G.A. and Hostager, B.S. CD40 Molecule Page, AfCS Signaling Gateway. Nature Online Page A000031, 2006.

Munroe, M.E. and Bishop, G.A. A costimulatory function for T cell CD40. J. Immunol. 178:671-682, 2007.

Munroe, M.E., Arbiser, J.L. and Bishop, G.A. Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis. J. Immunol. 179:753-763, 2007.

Xie, P., Stunz, L.L., Larison, K.D., Yang, B. and Bishop, G.A. TRAF3 is a critical regulator of B cell homeostasis in secondary lymphoid organs. Immunity 27:253-267, 2007.

Rahhal, R., VandenBush, T.J., McLendon, M.K., Apicella, M.A. and Bishop, G.A. Differential effects of Francisella tularensis lipopolysaccharide on B lymphocytes. J. Leuk. Biol. 82:813-820, 2007

Rowland, S.L., Tremblay, M.M., Ellison, J.M., Stunz, L.L., Bishop, G.A. and Hostager, B.S. A novel mechanism for TRAF6-dependent CD40 signaling. J. Immunol. 179:4645-4653, 2007.

Bishop, G.A. and Xie, P. Multiple roles of TRAF3 signaling in lymphocyte function. Immunol. Res. 39:22-32, 2007.

Bishop, G.A., Moore, C.R., Xie, P., Stunz, L.L. and Kraus, Z.J. TRAF proteins in CD40 signaling. Adv. Exp. Med. Biol. 597:131-151, 2007.

VandenBush, T.J. and Bishop, G.A. TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation. Eur. J. Immunol. 38:400-409, 2008.

Peters, A.L., Plenge, R., Graham, R., Altshuler, D., Moser, K., Gaffney, P.M. and Bishop, G.A. A novel polymorphism of the human CD40 receptor with enhanced function. Blood. In press, 2008.

Xue, H., Jing, X., Zhao, D., Haring, J.S., Bollenbacher-Reilley, J., Yang, B., Liu, C., Bishop, G.A., Harty, J.T. and Leonard, W.J. Targeting the GABPB1L isoforms does not perturb lymphocyte development and function. Mol. Cell Biol., in press, 2008.

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