Kin Fai Au's publications

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    Human tRNA synthetase catalytic nulls with diverse functions.
    Lo, W.S., Gardiner E., Xu, Z., Lau C.F., Wang, F., Zhou, J.J., Mendlein, J.D., Nangle, L.A., Chiang, K.P., Yang, X.L., Au, Kin Fai, Wong, W.H., Guo, M., Zhang, M., Schimmel, P.
    Science. 2014 Jul 18. 345 (6194), 328-32 [Manuscript]


    ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
    Qiu H., Lee S., Shang Y., Wang W.Y., Au, Kin Fai, Kamiya S., Barmada S.J., Finkbeiner S., Lui H., Carlton C.E., Tang A.A., Oldham M.C., Wang H., Shorter J., Filiano A.J., Roberson E.D., Tourtellotte W.G., Chen B., Tsai L.H., Huang E.J.
    The Journal of clinical investigation. 2014 Feb 10. 124 (3), 0-0 [Manuscript]


    Characterization of the human ESC transcriptome by hybrid sequencing
    Au, Kin Fai, Sebastiano V., Afshar P.T., Durruthy J.D., Lee L., Williams B.A., Bakel H.V., Schadt E., Pera R.A.R., Underwood J., Wong W.H.
    Proc. Natl. Acad. Sci. USA 2013 110 (50) E4821-E4830 [Manuscript]


    Improving PacBio long read accuracy by short read alignment.
    Au, Kin Fai, Underwood, J., Lee, L., Wong, W.H.
    PLoS ONE 2012. 7(10): e46679. doi:10.1371/journal.pone.0046679 [Manuscript]


    RNA sequencing reveals diverse and dynamic repertoire of the Xenopus tropicalis transcriptome over development.
    Tan, M.H.*, Au, Kin Fai*, Yablonovitch, A.L.*, Wills, A.E., Baker J.C., Wong, W.H., Li, J.B.
    Genome Research, 2012. doi:10.1101/gr.141424.112 [Manuscript]
    * These authors contributed equally to this work


    Activation of Innate Immunity is Required for Efficient Nuclear Reprogramming
    Lee, J., Sayed, N., Hunter, A., Au, Kin Fai, Wong, W.H., Mocarski, E., Pera, R.R., Yakubov, E., Cooke, J.P.
    Cell. 2012 Oct 26. 151 (3):547-58 [Manuscript]


    Oct4-Sall4-Nanog network controls developmental progression in the preimplantation mouse embryo
    Tan, M.H.*, Au, Kin Fai*, Leong, D.E., Foygel. K., Wong, W.H., Yao, M.W.M.
    Molecular Systems Biology. 2013. 9:632. [Manuscript]
    * These authors contributed equally to this work


    Detection of splice junctions from paired-end RNA-seq data by SpliceMap
    Au, Kin Fai, Jiang, H., Lin, L., Xing, Y., Wong, W.H.
    Nucleic Acids Research. Aug;38(14):4570-8. 2010. [Manuscript]


    Structures of an alanine racemase from Bacillus anthracis (BA0252) in the presence and absence of (R)-1-aminoethylphosphonic acid (L-Ala-P)
    Au, Kin Fai, Ren, J., Walter, T.S., Harlos, K., Nettleshipa, J.E., Owens, R.J., Stuart, D.I., Esnouf, R.M.
    Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 May 1;64(Pt 5):327-33. Aug;[Manuscript]


    Application of high-throughput technologies to a structural proteomics-type analysis of Bacillus anthracis
    Au, Kin Fai, Berrow, N.S., Blagova, E., Boucher, I.W., Boyle, M.P., Brannigan, J.A., Carter, L.G., Dierks, T., Folkers, G., Grenha, R., Harlos, K., Kaptein, R., Kalliomaa, A.K., Levdikov, V.M., Meier, C., Milioti, N., Moroz, O., Muller, A., Owens, R.J., Rzechorzek, N., Sainsbury, S., Stuart, D.I., Walter, T.S., Waterman, D.G., Wilkinson, A.J., Wilson, K.S., Zaccai, N., Esnouf, R.M., Fogg, M.J.
    Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1267-75.[Manuscript]


    Lysine methylation as a routine rescue strategy for protein crystallization
    Walter, T.S., Meier, C., Assenberg, R., Au, Kin Fai, Ren, J., Vermaa, A., Nettleshipa, J.E., Owens, R.J., Stuart, D.I., Grimes, J.M..
    Structure. 2006 Nov;14(11):1617-22.[Manuscript]