Au Lab

Research Focus


Collaborators

Currently, we have very close ongoing collobrations with:


Latest Publications


A novel primate-specific noncoding RNA modulates human embryo- and pluripotent stem cell fate.
Durruthy-Durruthy J., Sebastiano V., Wossidlo M., Cepeda D., Cui J., Grow E.J., Davila J., Mall M., Wing W.H., Wysocka J., Au, K.F., Pera, R.R.
Nature Genetics. 2015. [Manuscript]


PacBio Sequencing and Its Applications.
Rhoads, A., Au, K.F.
Genomics, Proteomics, & Bioinformatics. 2015. [Manuscript]


Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing.
Weirather, J.*, Afshar, P.T.*, Clark, T., Tseng, E., Powers, L., Underwood, J.G., Zabner, J., Korlach, J., Wong, W.H., Au, K.F.
Nucleic Acids Research. 2015 [Manuscript]
* These authors contributed equally to this work


Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis.
Xu, Z., Peters, R.J., Weirather, Jason, Luo, H., Liao, B., Zhang, X., Zhu, Y., Ji, A., Zhang, B., Hu, S., Au, Kin Fai, Song, J., Chen, S.
The Plant Journal. 2015 Apr 24 [Manuscript]


The transcriptome of human pluripotent stem cells.
Au, Kin Fai*, Sebasiano, V.
Current Opinion in Genetics and Development. 2014 Oct 31. 28, 71-77 [Manuscript]
* Corresponding Author


News

05-26-2016: IDP-ASE, a tool for haplotyping and quantifying allele-specific expression from Second Generation Sequencing and PacBio sequencing, is released.

04-11-2016: Update to LSC (version 2.0), the long read error correction tool, is released.

01-21-2016: HPAT Transcripts highlighted in Nature technology feature

"Finding function in mystery transcripts" by Kelly Rae Chi

08-18-2015: American Cancer Society (ACS) Seed Grants for Junior Faculty (IRG-77-004-34) is awarded

12-16-2015: PhRMA Foundation Research Starter Grant is awarded

http://www.phrmafoundation.org/2015-awards/research-starter-grants/informatics/

08-18-2015: American Cancer Society (ACS) Seed Grants for Junior Faculty (IRG-77-004-34) is awarded

05-26-2015: IDP-fusion paper is released paper is released

Jason L. Weirather*, Pegah Tootoonchi Afshar*, Tyson A. Clark, Elizabeth Tseng, Linda S. Powers, Jason Underwood, Joseph Zabner, Jonas Korlach, Wing Hung Wong and Kin Fai Au
Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing [preprint]
*These authors contributed equally to this work.

02-02-2015: Minor updates and bug fixes to LSC 1.beta

Feature Updates:

Bug Fixes: