Justin Grobe, Ph.D.

Postdoctoral Fellow (2006-current)

 

Publications from Sigmund Lab

Preservation of intracellular renin expression is insufficient to compensate for genetic loss of secreted renin.

Xu D, Borges GR, Grobe JL, Pelham CJ, Yang B, Sigmund CD.

Hypertension. 2009 Dec;54:1240-1247.

PMID: 19822797

 

PPARgamma differentially regulates energy substrate handling in brown vs. white adipose.

Grobe JL, Venegas-Pont M, Sigmund CD, Ryan MJ.

Am J Physiol Regul Integr Comp Physiol. 2009 ;296:R1325-R1326.

PMID: 19261916

 

An intracellular renin-angiotensin system in neurons: fact, hypothesis, or fantasy.

Grobe JL, Xu D, Sigmund CD.

Physiology (Bethesda). 2008;23:187-193.

PMID: 18697992

Representative Publications From Graduate Work

1: Grobe JL, Mecca AP, Mao H, Katovich MJ.  
  Chronic angiotensin-(1-7) prevents cardiac fibrosis in DOCA-salt model of hypertension.
Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2417-23. Epub 2006 Jan 13.
2: Grobe JL, Katovich MJ.  
  Alterations in aortic vascular reactivity to angiotensin 1-7 in 17-beta-estradiol-treated female SD rats.
Regul Pept. 2006 Jan 15;133(1-3):62-7. Epub 2005 Oct 10.
3: Huentelman MJ, Grobe JL, Vazquez J, Stewart JM, Mecca AP, Katovich MJ, Ferrario CM, Raizada MK.  
  Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats.
Exp Physiol. 2005 Sep;90(5):783-90. Epub 2005 Jul 27.
4: Katovich MJ, Grobe JL, Huentelman M, Raizada MK.  
  Angiotensin-converting enzyme 2 as a novel target for gene therapy for hypertension.
Exp Physiol. 2005 May;90(3):299-305. Epub 2005 Jan 7. Review.
5: Grobe J, Rowland N, Katovich M.  
  Role of angiotensin II and the subfornical organ in the pharmacological actions of ethanol.
Alcohol Alcohol. 2004 Sep-Oct;39(5):410-7. Epub 2004 Aug 2.

Back to Members