The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Drugs of Abuse Screen
Order Code: DAU
Epic Lab Code: LAB500
Order Form: A-1a Miscellaneous Request or Epic Req
  Chemistry
6240 RCP
356-3527
Specimen:
Urine
Collection Medium:
Urine - Random urine container
Minimum:
10 mls random urine
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Analytic Time:
2 hours (upon receipt in laboratory)
Reference Range:
None
Comments:
Screen includes amphetamines, barbiturates, benzodiazepines, cocaine, 
opiates, tetrahydrocannabinoids (THC).  A presumptive positive result 
for any of the tested drugs indicates the possible presence of the drug 
or metabolites in the urine, but does not measure the level of 
intoxication.

If confirmation is needed for amphetamines, barbiturates, 
benzodiazepines, cocaine, opiates, and tetrahydrocannabinoids (THC), 
call the Laboratory at 356-3527.  Allow up to seven days for 
confirmatory results.  Confirmation is at an additional charge.

Test Cut-off Concentrations (ng/ml)
Amphetamines                  1000
Barbiturates                   200
Benzodiazepine                 100
Cocaine                        300
Opiate                         300
THC                             50

References:

Belson MG, Simon HK, Sullivan K, Geller RJ.  The Utility of Toxicologic 
Analysis in Children with Suspected Ingestion.  Pediatr Emerg Care 
1999;15:383-387.

Bast RP, Helmer SD, Henderson SR, Rogers MA, Shapiro WM, Smith RS.  
Limited Utility of Routine Drug Screening in Trauma Patients.  South 
Med J 2000;93:397-399.

De La Torre R, Domino-Salvany A, Badia R, Gonzalez G, McFarlane D, San 
L, Torrens M.  Clinical Evaluation of the Triage Analytical Device for 
Drugs-of-Abuse Testing.  Clinical Chemistry 1996;42(9):1433-1438.

Hammett-Stabler CA, Pesce AJ, Cannon DJ.  Urine Drug Screening in the 
Medical Setting.  Clinica Chimica Acta 2002;315:125-135.

Schiller MJ, Shumway M, Batki SL.  Utility of Routine Drug Screening in 
a Psychiatric Emergency Setting.  Psychiatric Services 2000;51:474-478.

Sugarman JM, Rodgers GC, Paul RI.  Utility of Toxicology Screening in a 
Pediatric Emergency Department.  Pediatric Emergency Care.  Pediatric 
Emergency Care 1997;13(3):194-197.
Test
Limitations:
There is the possibility that other substances and/or factors may 
interfere with the test and cause erroneous results (e.g., technical or 
procedural errors).  Call the lab at 319-356-3527 for additional 
information.  See appendix "Cross Reacting Drugs".
Methodology:
Online DAT automated assays are based on the kinetic interaction of 
microparticles in a solution (KIMS) as measured by changes in light 
transmission.
CPT Code:
80101 x6
 
See also:
Barbiturate Confirmation, Random Urine
Benzodiazepine Confirmation, Random Urine
Cocaine Confirmation, Urine
Drugs of Abuse Screen Confirmation, Urine
Opiates (Drugs of Abuse Confirmation/Quantitation), Random Urine
THC Confirmation, Random Urine
 
See Additional Information:
Cross Reacting Drugs

Alphabetic main page

Updated: 11/17/2009

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.