The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Metanephrines
Order Code: METNBSU
Epic Lab Code: LAB409
Order Form: A-1a General Lab or Epic Req
  Commercial "Mail-out" Laboratory
6240 RCP
356-3527
Specimen:
Urine More information
Collection Medium:
Urine - 24 hour/timed urine glass container with acid
Minimum:
For peds, contact Pharmacy for correct amount of concentrated HCl.
Children 5 years and under suggest: 1 mL 6 N HCl for every 100 mL urine 
produced.

Adult minimum:  10 mL of a well-mixed 24 hr urine collected with 25 mL 
6N HCl as preservative (preferred) or random urine.
Pediatric minimum:  5 mL aliquot of 24 hr collection.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after
collection period is completed.
Analytic Time:
2 weeks
Reference Range:
By report.
Comments:
If screening for Neuroblastoma, the following tests need to be ordered: 
CATNBSU (Catecholamines, Fractionated), DOPNBSU (Dopamine), HVANBSU 
(Homovanillic Acid), METNBSU (Metanephrines), VMANBSU (Vanillylmandelic 
Acid).

Collection containers available from Pharmacy.  VMA, catecholamines and 
metanephrines may be done on same collection. Propranolol (Inderal) 
will falsely lower total metanephrines. Labetalol (Normodyne) can 
falsely elevate the apparent concentration of urine metanephrines.  
Creatinine done on sample at no additional charge.
CPT Code:
82570, 83835
 
See also:
Catecholamines, Fractionated, Urine
Dopamine, Urine
Homovanillic Acid (HVA), Urine
Neuroblastoma Screen, Urine
Vanillylmandelic Acid (VMA), Urine
 
See Additional Information:
Urine Tests Requiring Preservatives, Refrigeration or Special Containers

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Updated: 11/18/2009

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.