CD1 recognition by human γδ T cells

We also study a third class of nonpeptide antigens, lipids and glycolipids presented by CD1. CD1 proteins are MHC-like-molecules that are specialized for the presentation lipids. We now find that γδ T cells in the major tissue subset recognize self and foreign lipids presented by CD1. We are isolating additional CD1-specific γδ T cells and identifying their lipid antigens.

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