Publications 2004-present

Barabanova, Y.A., Kang, H.-K., Myoung, J., Kang, B.S., Bishop, G.A. and Kim, B.S. Role of the MHC class II transmembrane region in antigen presentation and intracellular trafficking. Immunology 111:165-172, 2004.

Haxhinasto, S. and Bishop, G.A. Synergistic B cell activation by CD40 and the B cell antigen receptor: Role of BCR-mediated kinase activation and TRAF regulation. J. Biol. Chem. 279:2575-2582, 2004.

Xie, P., Hostager, B.S. and Bishop, G.A. Requirement for TRAF3 in signaling by LMP1, but not CD40, in B lymphocytes. J. Exp. Med. 199:661-671, 2004.

Stunz, L.L., Busch, L.K., Munroe, M.E., Sigmund, C.D., Tygrett, L.T., Waldschmidt, T.J., and Bishop, G.A. Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture. Immunity 21:255-266, 2004.

Xie, P. and Bishop, G.A. Roles of TRAF3 in signaling by CTAR1 and CTAR2 of LMP1. J. Immunol. 173:5546-5555, 2004.

Bishop, G.A. “The multifaceted roles of TRAFs in the regulation of B lymphocyte function”, invited review for Nature Reviews in Immunology 4:775-786, 2004.

Munroe, M.E. and Bishop, G.A. Role of TRAF2 in distinct and overlapping CD40 and TNFR2/CD120b-mediated B lymphocyte activation. J. Biol. Chem. 279:53222-53231, 2004.

Mukundan, L. Bishop, G.A., Head, K.Z., Zhang, L., Wahl, L.M. and Suttles, J. TRAF6 is an essential mediator of CD40-activated pro-inflammatory pathways in monocytes and macrophages. J. Immunol. 174:1081-1090, 2005.

Bishop, G.A. and Lamb, J.R. Lymphocyte activation: Editorial overview. Curr. Opin. in Immunology (invited editors) 17: 1-3, 2005.

Moore, C.R. and Bishop, G.A. Differential regulation of CD40-mediated TRAF degradation in B lymphocytes. J. Immunol. 175:3780-3789, 2005

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Wu, S., Xie, P., Welsh, K., Li, C., Ni, C., Zhu, X., Reed, J.C., Satterthwait, A.C., Bishop, G.A. and Ely, K.R. LMP1 protein from EBV is a structural decoy in B lymphocytes for binding to TRAF3. J. Biol. Chem. 280:33620-33626, 2005.

Andrade, R.M., Wessendarp, M., Portillo, J.C., Yang, J., Gomez, F.J., Durbin, J.E., Bishop, G.A. and Subuaste, C.S. TRAF6-dependent CD40 signaling primes macrophages to acquire anti-microbial activity in response to TNF-a . J. Immunol. 175:6015-6021, 2005.

Bishop, G.A. CD40 and its viral mimic LMP1. Modern Aspects of Immunobiology 16:6, 2005.

Xie, P., Hostager, B.S., Munroe, M.E., Moore, C.R. and Bishop, G.A. Cooperation between TRAFs 1 and 2 in CD40 signaling. J. Immunol. 176:5388-5400, 2006.

Benson, R., Hostager, B.S. and Bishop, G.A. Rapid CD40-mediated rescue from CD95-induced apoptosis requires TRAF6 and PI3K. Eur. J. Immunol. 36:2535-2543, 2006.

Bishop, G.A. and Hostager, B.S. CD40 Molecule Page, AfCS Signaling Gateway. Nature Online Page A000031, 2006.

Munroe, M.E. and Bishop, G.A. A costimulatory function for T cell CD40. J. Immunol. 178:671-682, 2007.

Munroe, M.E., Arbiser, J.L. and Bishop, G.A. Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis. J. Immunol. 179:753-763, 2007.

Xie, P., Stunz, L.L., Larison, K.D., Yang, B. and Bishop, G.A. TRAF3 is a critical regulator of B cell homeostasis in secondary lymphoid organs. Immunity 27:253-267, 2007.

Rahhal, R., VandenBush, T.J., McLendon, M.K., Apicella, M.A. and Bishop, G.A. Differential effects of Francisella tularensis lipopolysaccharide on B lymphocytes. J. Leuk. Biol. 82:813-820, 2007

Rowland, S.L., Tremblay, M.M., Ellison, J.M., Stunz, L.L., Bishop, G.A. and Hostager, B.S. A novel mechanism for TRAF6-dependent CD40 signaling. J. Immunol. 179:4645-4653, 2007.

Bishop, G.A. and Xie, P. Multiple roles of TRAF3 signaling in lymphocyte function. Immunol. Res. 39:22-32, 2007.

Bishop, G.A., Moore, C.R., Xie, P., Stunz, L.L. and Kraus, Z.J. TRAF proteins in CD40 signaling. Adv. Exp. Med. Biol. 597:131-151, 2007.

VandenBush, T.J. and Bishop, G.A. TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation. Eur. J. Immunol. 38:400-409, 2008.

Xie, P., Kraus, Z.J., Stunz, L.L. and Bishop, G.A. Roles of TRAF molecules in B lymphocyte function. Cytokine & Growth Factor Reviews 19:199-207, 2008.

Peters, A.L., Plenge, R., Graham, R., Altshuler, D., Moser, K., Gaffney, P.M. and Bishop, G.A. A novel polymorphism of the human CD40 receptor with enhanced function. Blood 112:1863-1871, 2008.

Xue, H., Jing, X., Zhao, D., Haring, J.S., Bollenbacher-Reilley, J., Yang, B., Liu, C., Bishop, G.A., Harty, J.T. and Leonard, W.J. Targeting the GABPb1L isoforms does not perturb lymphocyte development and function. Mol. Cell Biol. 28:4300-4309, 2008.

Kraus, Z.J., Haring, J.S. and Bishop, G.A. TRAF5 is required for optimal T cell expansion and survival in response to infection. J. Immunol. 181:7800-7809, 2008.

Hildebrand, J., Xie, P. and Bishop, G.A. Signal transduction by receptors for BAFF and APRIL. In Blys Ligands and Receptors, M. Cancro, Ed., Humana Press, Totowa, NJ. Chapter 5, p. 93-114, 2009.

Graham, J.P., Moore, C.R. and Bishop, G.A. Roles of the TRAF2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, LMP1. J. Immunol. 183:2966-2973, 2009.

Poovassery, J.S., Vanden Bush, T.J., and Bishop, G.A. Antigen receptor signals rescue B cells from TLR tolerance. J. Immunol. 183:2974-2983, 2009.

Peters, A.L., Stunz, L.L. and Bishop, G.A. CD40 and autoimmunity: The dark side of a great activator. Seminars in Immunol. (G.A. Bishop, Guest Editor) 21:293-300, 2009.

Kraus, Z.J., Nakano, H. and Bishop, G.A. TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40. Proc. Natl. Acad. Sci. (USA) 106:17140-17145, 2009.

Vanden Bush, T.J., Buchta, C.M., Claudio, J. and Bishop, G.A. Cutting Edge: Importance of IL-6 and cooperation between innate and adaptive immune receptors in cellular vaccination with B lymphocytes. J. Immunol. 183:4833-4837, 2009.

Tseng, W., Lu, J., Bishop, G.A., Watson, A.D., Sage, A.P., Demer, L., and Tintut, Y. Regulation of IL-6 expression in osteoblasts by oxidized phospholipids. J. Lipid. Res. 51:1010-1016, 2010.

Graham, J.P., Arcipowski, K.M. and Bishop, G.A. Differential B lymphocyte regulation by CD40 and its viral mimic, LMP1. Immunological Reviews 237:226-248, 2010.

Peters, A.L., Stunz, L.L., Meyerholz, D.K., Mohan, C. and Bishop, G.A. LMP1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle mice. J. Immunol. 185:4053-4062, 2010.

Munroe, M.E., Businga, T.E., Kline, J.N. and Bishop, G.A. Anti-inflammatory effects of the neurotransmitter agonist Honokiol, in a mouse model of asthma. J. Immunol. 185:5586-5597, 2010.

Hildebrand, J.M., Luo, Z. Manske, M.K., Price-Troska, T., Ziesmer, S.C., Lin, W., Hostager, B.S., Slager, S., Witzig, T.E., Ansell, S.M., Cerhan, J.R., Bishop, G.A.* and Novak, A.J.* (*co-senior authors). A BAFF-R mutation associated with non-Hodgkin lymphoma exhibits altered TRAF recruitment and reveals new insights into proximal BAFF-R signaling. J. Exp. Med. 207:2569-2579, 2010.

Peters, A.L. and Bishop, G.A. Differential TRAF3 utilization by a variant human CD40 with enhanced signaling. J. Immunol. 185:6555-6562, 2010.

Xie, P., Kraus, Z.J., Stunz, L.L., Liu, Y. and Bishop, G.A. TRAF3 is required for T cell-mediated immunity and TCR/CD28 signaling. J. Immunol. 186:143-155, 2011.

Decker, D.A., Hostager, B.S. and Bishop, G.A. CD40 signaling. Chapter for Encyclopedia of Signaling Molecules, Sangdun Choi, Editor, Springer Press. In press, 2011.

Arcipowski, K.M., Stunz, L.L., Graham, J.P., Kraus, Z.J., Vanden Bush, T.J. and Bishop, G.A. Molecular mechanisms of TNFR-associated factor 6 (TRAF6) utilization by the oncogenic viral mimic of CD40, latent membrane protein 1 (LMP1). J. Biol. Chem. 286:9948-9955, 2011.

Vanden Bush, T.J. and Bishop, G.A. CDK-mediated regulation of cell functions via c-Jun phosphorylation and AP-1 activation. PLoS One 6(4): e19468. doi:10.1371/journal.pone.0019468, 2011.

Hildebrand, J.M., Yi, Z., Buchta, C.M., Poovassery, J., Stunz, L.L. and Bishop, G.A. TRAF3 and TRAF5 in immune regulation. Invited review for Immunological Reviews 244:55-74, 2011.

Xie, P., Poovassery, J., Stunz, L.L., Smith, S.M., Schultz, M.L., Carlin, L.C. and Bishop, G.A. Enhanced TLR responses of TRAF3-deficient B lymphocytes. J. Leuk. Biol. 90: 1149-1157, 2011.

Bishop, G.A. The power of mAbs as agents of discovery: CD40 revealed as a B lymphocyte costimulator. Invited “Pillars of Immunology” article for The Journal of Immunology 188:4127-4129, 2012.

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